Journal
ACS NANO
Volume 4, Issue 11, Pages 6318-6322Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nn100760f
Keywords
localized surface plasmon resonance; nanoparticle; nanostar; biosensing; streptavidin; biotin
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Funding
- German Excellence Initiative of the Deutsche Forschungsgemeinschaft (DFG) via the Nanosystems Initiative Munich (NIM)
- Alexander von Humboldt Foundation
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Gold nanostars provide high sensitivity for single nanoparticle label free biosensing The nanostars present multiple plasmon resonances of which the lower energy ones, corresponding to the nanostar tips and core-tip interactions are the most sensitive to environmental changes streptavidin molecules are detected upon binding to individual biotin modified gold nanostars by spectral shifts in the plasmon resonances Concentrations at low as 0 1 nM produce a shift of the tip related plasmon resonances of about 2 3 nm (5 3 meV)
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