4.8 Article

Functional Cationic Nanomagnet - Porphyrin Hybrids for the Photoinactivation of Microorganisms

Journal

ACS NANO
Volume 4, Issue 12, Pages 7133-7140

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/nn1026092

Keywords

porphyrins; cationic; nanomagnets; photoinactivation; microorganisms; hybrid materials

Funding

  1. University of Aveiro
  2. Fundacao para a Ciencia e a Tecnologia (FCT)
  3. FEDER

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Cationic nanomagnet porphyrin hybrids were synthesized and their photodynamic therapy capabilities were investigated against the Gram (-) Escherichia coli bacteria, the Gram (+) Enterococcus faecalis bacteria and T4-like phage. The synthesis, structural characterization, photophysical properties, and antimicrobial activity of these new materials are discussed. The results show that these new multicharged nanomagnet porphyrin hybrids are very stable in water and highly effective in the photoinactivation of bacteria and phages. Their remarkable antimicrobial activity, associated with their easy recovery, just by applying a magnetic field, makes these materials novel photosensitizers for water or wastewater disinfection.

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