Journal
ACS NANO
Volume 3, Issue 5, Pages 1190-1202Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nn800836f
Keywords
nanoparticle cluster arrays; SERS; bacterial pathogen detection; template-guided self-assembly; nanofabrication; photonic-plasmonic resonances
Categories
Funding
- Department of Defense [W91NF-06-2-0040]
Ask authors/readers for more resources
Defined nanoparticle cluster arrays (NCAs) with total lateral dimensions of up to 25.4 mu m x 25.4 mu m have been fabricated on top of a 10 nm thin gold film using template-guided self-assembly. This approach provides precise control of the structural parameters in the arrays, allowing a systematic variation of the average number of nanoparticles in the clusters (n) and the edge-to-edge separation (Lambda) between 1 < n < 20 and 50 nm <= Lambda <= 1000 nm, respectively. Investigations of the Rayleigh scattering spectra and surface-enhanced Raman scattering (SERS) signal intensities as a function of n and A reveal direct near-field coupling between the particles within individual clusters, whose strength increases with the cluster size (n) until it saturates at around n = 4. Our analysis shows that strong near-field interactions between individual clusters significantly affect the SERS signal enhancement for edge-to-edge separations Lambda < 200 nm. The observed dependencies of the Raman signals on n and Lambda indicate that NCAs support a multiscale signal enhancement which originates from simultaneous inter- and intracluster coupling and vertical bar E vertical bar-field enhancement. The NCAs provide strong and reproducible SERS signals not only from small molecules but also from whole bacterial cells, which enabled a rapid spectral discrimination between three tested bacteria species: Escherichia coli, Bacillus cereus, and Staphylococcus aureus.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available