4.8 Article

High-Photoluminescence-Yield Gold Nanocubes: For Cell Imaging and Photothermal Therapy

Journal

ACS NANO
Volume 4, Issue 1, Pages 113-120

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/nn901064m

Keywords

gold nanocubes; photoluminescence; cell imaging; photothermal therapy

Funding

  1. Shanghai Municipal Science and Technology Commission [06ZR14005]
  2. National Natural Science Foundation of China [110774027]

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Gold nanocubes demonstrate unique optical properties of the high photoluminescence (PL) quantum yield and a remarkably enhanced extinction band at 544 nm. The 4 X 10(-2) PL yield, which is about 200 times higher than that of gold nanorods, allows gold nanocubes to be successfully used in cell imaging of human liver cancer cells (QGY) and human embryo kidney cells (293T) with a common method of single-photon excitation. The high extinction coefficients of gold nanocubes also facilitate them carrying out the photothermal therapy of QGY and 293T cells, showing similar photokilling efficiency as compared to gold nanorods.

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