Journal
ACS NANO
Volume 2, Issue 2, Pages 197-202Publisher
AMER CHEMICAL SOC
DOI: 10.1021/nn700344x
Keywords
silica microspheres; superparamagnetic; fluorescent; iron oxide nanoparticles; quantum dots; magnetic manipulation; multifunctional microspheres
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Funding
- NCI NIH HHS [1U54-CA119349] Funding Source: Medline
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We describe the synthesis of magnetic and fluorescent silica microspheres fabricated by incorporating maghemite (gamma-Fe2O3) nanoparticles (MPs) and CdSe/CdZnS core/shell quantum dots (QDs) into a silica shell around preformed silica microspheres. The resultant similar to 500 nm microspheres have a narrow size distribution and show uniform incorporation of QDs and MPs into the shell. We have demonstrated manipulation of these microspheres using an external magnetic field with real-time fluorescence microscopy imaging.
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