Journal
ACS CHEMICAL BIOLOGY
Volume 3, Issue 2, Pages 84-86Publisher
AMER CHEMICAL SOC
DOI: 10.1021/cb8000217
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In addition to their classic role in cell motility, certain cilia have sensory or signaling functions. In sea urchin embryos, short motile cilia randomly propel the early embryo, while a group of long, immotile cilia appear later, coincident with directional swimming and localized within a region that gives rise to the larval nervous system. Motile cilia can be selectively removed by treatment with a novel derivative of dillapiol, leaving the putative sensory cilia for comparative investigation and a gently deciliated embryo ready for studies of regeneration signaling.
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