Journal
ACS APPLIED MATERIALS & INTERFACES
Volume 10, Issue 41, Pages 34991-34999Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsami.8b14370
Keywords
optical biosensing; nanoporous films; Goos-Hanchen shift; surface plasmons; flexible substrates; wet chemistry free; biotin-streptavidin model
Funding
- Singapore Ministry of Education (MOE) [MOE2015-T2-2-103]
- A-Star Singapore-China JRP [1420200046]
- NUS-Biomedical Institute for Global Health Research and Technology
Ask authors/readers for more resources
The development of various plasmonic nanoporous materials has attracted much interest in different areas of research including bioengineering and biosensing because of their large surface area and versatile porous structure. Here, we introduce a novel technique for fabricating silver-stibnite nanoporous plasmonic films. Unlike conventional techniques that are usually used to fabricate nanoporous plasmonic films, we use a room-temperature growth method that is wet-chemistry free, which enables wafer-scale fabrication of nanoporous films on flexible substrates. We show the existence of propagating surface plasmon polaritons in nanoporous films and demonstrate the extreme bulk refractive index sensitivity of the films using the Goos Hanchen shift interrogation scheme. In the proof-of-concept biosensing experiments, we functionalize the nanoporous films with biotin-thiol using a modified functionalization technique, to capture streptavidin. The fractal nature of the films increases the overlap between the local field and the immobilized biomolecules. The extreme sensitivity of the Goos Hanchen shift allows femtomolar concentrations of streptavidin to be detected in real time, which is unprecedented using surface plasmons configuration.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available