Journal
ACS APPLIED MATERIALS & INTERFACES
Volume 10, Issue 37, Pages 31136-31145Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsami.8b11648
Keywords
black phosphorus; photoluminescence; FLIM; Raman mapping; silicon dioxide coating
Funding
- National Natural Science Foundation of China [61378088, 61575010, 51671006]
- fund for Biophotonics Innovative Personnel Base Construction [BIPB 101000541212011]
- Beijing University of Technology [AMF 101000541213504]
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Black phosphorus (BP) has attracted much attention as a new member of 2D materials due to its unique electronic and optical properties and a wide range of promising applications. Here, for the first time, we report the photoluminescence lifetime of BP nanomaterial and its applications as an efficient agent for live cell imaging. With a lateral size of similar to 35 nm and a thickness of similar to 6 nm, the fabricated BP nanoparticles (BPNPs) exhibited a unique photoluminescent (PL) emission at similar to 690 nm. The photoluminescence lifetime (PLT) of BPNPs was determined to be 110.5 ps. Coating a layer of mesoporous silica on the surface of BPNPs (BPNPs@mSiO(2)) extended the lifetime to 267 ps, suggesting a change in the microenvironment. The lifetime was also influenced by ionic strength and intracellular microenvironment, which implies BPNPs as valuable probes for sensing variations in the microenvironment. Live cell imaging was achieved via directly probing the photoluminescence intensity or the photoluminescence lifetime. Our findings are significant, implying that BPNPs can be of large value in sensing variations of the cellular microenvironment and in probing cells with distinct cytosolic contents. This research leads to promising prospects for BPNPs in multiple biomedical applications.
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