Related references
Note: Only part of the references are listed.Viral RNA detection by RIG-I-like receptors
Mitsutoshi Yoneyama et al.
CURRENT OPINION IN IMMUNOLOGY (2015)
Necroptosis and its role in inflammation
Manolis Pasparakis et al.
NATURE (2015)
Response of host inflammasomes to viral infection
I-Yin Chen et al.
TRENDS IN MICROBIOLOGY (2015)
Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection
Donna A. MacDuff et al.
ELIFE (2015)
Gliotoxin Suppresses NF-κB Activation by Selectively Inhibiting Linear Ubiquitin Chain Assembly Complex (LUBAC)
Hiroki Sakamoto et al.
ACS CHEMICAL BIOLOGY (2015)
HOIL-1L Functions as the PKCζ Ubiquitin Ligase to Promote Lung Tumor Growth
Markus A. Queisser et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
RBR E3 ubiquitin ligases: new structures, new insights, new questions
Donald E. Spratt et al.
BIOCHEMICAL JOURNAL (2014)
Inflammatory outcomes of apoptosis, necrosis and necroptosis
Pavel Davidovich et al.
BIOLOGICAL CHEMISTRY (2014)
A catalytic-independent role for the LUBAC in NF-κB activation upon antigen receptor engagement and in lymphoma cells
Sonia M. Dubois et al.
BLOOD (2014)
E3 Ubiquitin Ligase HOIP Attenuates Apoptotic Cell Death Induced by Cisplatin
Craig MacKay et al.
CANCER RESEARCH (2014)
Ubiquitin in the immune system
Julia Zinngrebe et al.
EMBO REPORTS (2014)
Met1-linked ubiquitination in immune signalling
Berthe K. Fiil et al.
FEBS JOURNAL (2014)
Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN
Tsuyoshi Takiuchi et al.
GENES TO CELLS (2014)
The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation
Mary A. Rodgers et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
IFN-γ or IFN-α Ameliorates Chronic Proliferative Dermatitis by Inducing Expression of Linear Ubiquitin Chain Assembly Complex
Hironari Tamiya et al.
JOURNAL OF IMMUNOLOGY (2014)
Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice
Scott B. Berger et al.
JOURNAL OF IMMUNOLOGY (2014)
Mechanism Underlying IκB Kinase Activation Mediated by the Linear Ubiquitin Chain Assembly Complex
Hiroaki Fujita et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Binding of OTULIN to the PUB Domain of HOIP Controls NF-κB Signaling
Veronique Schaeffer et al.
MOLECULAR CELL (2014)
Molecular Basis and Regulation of OTULIN-LUBAC Interaction
Paul R. Elliott et al.
MOLECULAR CELL (2014)
Ubiquitination in disease pathogenesis and treatment
Doris Popovic et al.
NATURE MEDICINE (2014)
Linear ubiquitin chains: NF-κB signalling, cell death and beyond
Kazuhiro Iwai et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Chronic Proliferative Dermatitis in Sharpin Null Mice: Development of an Autoinflammatory Disease in the Absence of B and T Lymphocytes and IL4/IL13 Signaling
Christopher S. Potter et al.
PLOS ONE (2014)
The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells
P. Wu et al.
CELL DEATH & DISEASE (2014)
Essential Role of the Linear Ubiquitin Chain Assembly Complex in Lymphoma Revealed by Rare Germline Polymorphisms
Yibin Yang et al.
CANCER DISCOVERY (2014)
HOIP Deficiency Causes Embryonic Lethality by Aberrant TNFR1-Mediated Endothelial Cell Death
Nieves Peltzer et al.
CELL REPORTS (2014)
TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice
James A. Rickard et al.
ELIFE (2014)
Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
Snehlata Kumari et al.
ELIFE (2014)
Polyglucosan Body Myopathy Caused by Defective Ubiquitin Ligase RBCK1
Johanna Nilsson et al.
ANNALS OF NEUROLOGY (2013)
OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin
Kirstin Keusekotten et al.
CELL (2013)
Deubiquitinating Enzyme Specificity for Ubiquitin Chain Topology Profiled by Di-Ubiquitin Activity Probes
Joanna F. McGouran et al.
CHEMISTRY & BIOLOGY (2013)
Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells
Yoshiteru Sasaki et al.
EMBO JOURNAL (2013)
Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling
Rune Busk Damgaard et al.
EMBO MOLECULAR MEDICINE (2013)
Mechanisms of NOD-like Receptor-Associated Inflammasome Activation
Haitao Wen et al.
IMMUNITY (2013)
Dimerization and Ubiquitin Mediated Recruitment of A20, a Complex Deubiquitinating Enzyme
Timothy T. Lu et al.
IMMUNITY (2013)
Linear ubiquitination-mediated NF-κB regulation and its related disorders
Fuminori Tokunaga
JOURNAL OF BIOCHEMISTRY (2013)
Target Specificity of the E3 Ligase LUBAC for Ubiquitin and NEMO Relies on Different Minimal Requirements
Judith J. Smit et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling
Berthe Katrine Fiil et al.
MOLECULAR CELL (2013)
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis
Elena Rivkin et al.
NATURE (2013)
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
Benjamin Stieglitz et al.
NATURE (2013)
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
Christoph H. Emmerich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
SHARPIN Regulates Uropod Detachment in Migrating Lymphocytes
Jeroen Pouwels et al.
CELL REPORTS (2013)
Whole-genome DNA/RNA sequencing identifies truncating mutations in RBCK1 in a novel Mendelian disease with neuromuscular and cardiac involvement
Kai Wang et al.
GENOME MEDICINE (2013)
MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades
Siqi Liu et al.
ELIFE (2013)
Structure of a compact conformation of linear diubiquitin
Ahmed Rohaim et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2012)
The Ubiquitin Code
David Komander et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
Generation and physiological roles of linear ubiquitin chains
Henning Walczak et al.
BMC BIOLOGY (2012)
Inactivation of the Deubiquitinase CYLD in Hepatocytes Causes Apoptosis, Inflammation, Fibrosis, and Cancer
Kostas Nikolaou et al.
CANCER CELL (2012)
Linear Ubiquitination of NEMO Negatively Regulates the Interferon Antiviral Response through Disruption of the MAVS-TRAF3 Complex
S. Mehdi Belgnaoui et al.
CELL HOST & MICROBE (2012)
Signal transduction by tumor necrosis factor receptors
Lucia Cabal-Hierro et al.
CELLULAR SIGNALLING (2012)
Structural Aspects of Ubiquitin Binding Specificities
Qing-Shan Fu et al.
CURRENT PROTEIN & PEPTIDE SCIENCE (2012)
A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7
Kelly Verhelst et al.
EMBO JOURNAL (2012)
Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation
Fuminori Tokunaga et al.
EMBO JOURNAL (2012)
The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension
Judith J. Smit et al.
EMBO JOURNAL (2012)
A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex
Hirokazu Yagi et al.
EMBO REPORTS (2012)
LUBAC synthesizes linear ubiquitin chains via a thioester intermediate
Benjamin Stieglitz et al.
EMBO REPORTS (2012)
IκB kinase regulation of the TPL-2/ERK MAPK pathway
Thorsten Gantke et al.
IMMUNOLOGICAL REVIEWS (2012)
Regulation of NF-κB by deubiquitinases
Edward W. Harhaj et al.
IMMUNOLOGICAL REVIEWS (2012)
IκB Kinase 2 Regulates TPL-2 Activation of Extracellular Signal-Regulated Kinases 1 and 2 by Direct Phosphorylation of TPL-2 Serine 400
Karine Roget et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
Rune Busk Damgaard et al.
MOLECULAR CELL (2012)
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency
Bertrand Boisson et al.
NATURE IMMUNOLOGY (2012)
Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages
Yogesh Kulathu et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Diverse ubiquitin signaling in NF-κB activation
Kazuhiro Iwai
TRENDS IN CELL BIOLOGY (2012)
A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response
Suzanne Paz et al.
CELL RESEARCH (2011)
Inhibition of NF-kappa B Signaling Retards Eosinophilic Dermatitis in SHARPIN-Deficient Mice
Yanhua Liang et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2011)
Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction
Kyung-Soo Inn et al.
MOLECULAR CELL (2011)
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
Fuminori Tokunaga et al.
NATURE (2011)
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
Fumiyo Ikeda et al.
NATURE (2011)
Linear ubiquitination prevents inflammation and regulates immune signalling
Bjoern Gerlach et al.
NATURE (2011)
Caspase 8 inhibits programmed necrosis by processing CYLD
Marie Anne O'Donnell et al.
NATURE CELL BIOLOGY (2011)
SHARPIN is an endogenous inhibitor of β1-integrin activation
Juha K. Rantala et al.
NATURE CELL BIOLOGY (2011)
Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
Philipp Wild et al.
SCIENCE (2011)
CYLD: a tumor suppressor deubiquitinase regulating NF-kappa B activation and diverse biological processes
S-C Sun
CELL DEATH AND DIFFERENTIATION (2010)
c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling
Jasmin N. Dynek et al.
EMBO JOURNAL (2010)
Regulatory mechanisms involved in the control of ubiquitin homeostasis
Yoko Kimura et al.
JOURNAL OF BIOCHEMISTRY (2010)
Mutations of optineurin in amyotrophic lateral sclerosis
Hirofumi Maruyama et al.
NATURE (2010)
Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains
Shengkai Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Inhibition of NF-κB Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes
Noula Shembade et al.
SCIENCE (2010)
Signaling to NF-κB: Regulation by Ubiquitination
Ingrid E. Wertz et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
The Role of Ubiquitin in NF-kappa B Regulatory Pathways
Brian Skaug et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
Francisca E. Reyes-Turcu et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
RING Domain E3 Ubiquitin Ligases
Raymond J. Deshaies et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome
Daniel Finley
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
YoungSik Cho et al.
CELL (2009)
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
Sudan He et al.
CELL (2009)
Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation
Simin Rahighi et al.
CELL (2009)
The Multiple Layers of Ubiquitin-Dependent Cell Cycle Control
Katherine Wickliffe et al.
CHEMICAL REVIEWS (2009)
Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
David Komander et al.
EMBO REPORTS (2009)
The Structure and Conformation of Lys63-Linked Tetraubiquitin
Ajit B. Datta et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Nonproteolytic Functions of Ubiquitin in Cell Signaling
Zhijian J. Chen et al.
MOLECULAR CELL (2009)
Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
Tobias L. Haas et al.
MOLECULAR CELL (2009)
Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma
Mara Compagno et al.
NATURE (2009)
Involvement of linear polyubiquitylation of NEMO in NF-κB activation
Fuminori Tokunaga et al.
NATURE CELL BIOLOGY (2009)
Building ubiquitin chains: E2 enzymes at work
Yihong Ye et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Ubiquitin-binding domains - from structures to functions
Ivan Dikic et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Breaking the chains: structure and function of the deubiquitinases
David Komander et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
Duan-Wu Zhang et al.
SCIENCE (2009)
TNF-α induces two distinct caspase-8 activation pathways
Lai Wang et al.
CELL (2008)
Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes
Imsang Lee et al.
CELL (2008)
CYLD mutations in familial skin appendage tumours
S. Saggar et al.
JOURNAL OF MEDICAL GENETICS (2008)
Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD
Ato Wright et al.
DEVELOPMENTAL CELL (2007)
Tumor suppressor CYLD regulates JNK-Induced cell death in Drosophila
Lei Xue et al.
DEVELOPMENTAL CELL (2007)
Coordinated regulation of toll-like receptor and NOD2 signaling by k63-linked polyubiquitin chains
Derek W. Abbott et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Proteasome-independent functions of ubiquitin in endocytosis and signaling
Debdyuti Mukhopadhyay et al.
SCIENCE (2007)
Reduced expression of CYLD in human colon and hepatocellular carcinomas
Claus Hellerbrand et al.
CARCINOGENESIS (2007)
Impaired regulation of NF-κB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice
Jun Zhang et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Ubiquitin-binding domains
James H. Hurley et al.
BIOCHEMICAL JOURNAL (2006)
A ubiquitin ligase complex assembles linear polyubiquitin chains
Takayoshi Kirisako et al.
EMBO JOURNAL (2006)
Abnormal lymphoid organ development in immunodeficient mutant mice
R. Seymour et al.
VETERINARY PATHOLOGY (2006)
Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-κB signaling
Ramin Massoumi et al.
CELL (2006)
Genetics of skin appendage neoplasms and related syndromes
DA Lee et al.
JOURNAL OF MEDICAL GENETICS (2005)
Ubiquitin-binding domains
L Hicke et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
IE Wertz et al.
NATURE (2004)
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
DL Boone et al.
NATURE IMMUNOLOGY (2004)
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
TR Brummelkamp et al.
NATURE (2003)
CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members
E Trompouki et al.
NATURE (2003)
A proteomics approach to understanding protein ubiquitination
JM Peng et al.
NATURE BIOTECHNOLOGY (2003)
Death Receptor Activation Complexes It Takes Two to Activate TNF Receptor 1
M. Saeed Sheikh et al.
CELL CYCLE (2003)
Adult-onset primary open-angle glaucoma caused by mutations in optineurin
T Rezaie et al.
SCIENCE (2002)
Constitutive nuclear factor κB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells
RE Davis et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Activation by IKKα of a second, evolutionary conserved, NF-κB signaling pathway
U Senftleben et al.
SCIENCE (2001)
Selective degradation of ubiquitinated Sic1 by purified 26S proteasome yields active S phase cyclin-Cdk
R Verma et al.
MOLECULAR CELL (2001)
Shared pathways of IκB kinase-induced SCFβTrCP-mediated ubiquitination and degradation for the NF-κB precursor p105 and IκBα
V Heissmeyer et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Activation of the IκB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
L Deng et al.
CELL (2000)
Detecting and measuring cotranslational protein degradation in vivo
GC Turner et al.
SCIENCE (2000)
Identification of the familial cylindromatosis tumour-suppressor gene
GR Bignell et al.
NATURE GENETICS (2000)
Recognition of the polyubiquitin proteolytic signal
JS Thrower et al.
EMBO JOURNAL (2000)
Share Paper
