Journal
ACS APPLIED MATERIALS & INTERFACES
Volume 6, Issue 5, Pages 3600-3606Publisher
AMER CHEMICAL SOC
DOI: 10.1021/am4058309
Keywords
cyano-substituted diarylethlene derivatives; red fluorescent organic nanoparticles; antiaggregation-caused quenching; broad excitation wavelength; cell imaging
Funding
- National Science Foundation of China [21134004, 21201108, 51363016]
- National 973 Project [2011CB935700]
- China Postdoctoral Science Foundation [2013T60100, 2012M520243]
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Cyano-substituted diarylethlene derivatives ROMe (-H, -CF3) with different peripheral substituted groups were synthesized in high yield. Water-soluble red fluorescent organic nanoparticles (FONs) could be facilely prepared from them via hydrophobic interaction with polyoxyethylene-polyoxypropylene-polyoxyethylene triblock copolymer (Pluronic F127). The optical properties and surface morphology of the synthesized FONs were characterized, and their biocompatibilities as well as their applications in cell imaging were further investigated. We demonstrate that such red FONs exhibit antiaggregation-caused quenching properties, broad excitation wavelengths, excellent water dispersibilities, and biocompatibilities, Making them promising for cell imaging.
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