4.8 Article

Near-Infrared Emitting Fluorescent BODIPY Nanovesicles for in Vivo Molecular Imaging and Drug Delivery

Journal

ACS APPLIED MATERIALS & INTERFACES
Volume 6, Issue 18, Pages 16166-16173

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/am5042115

Keywords

nanovesicles; near-infrared; BODIPY; in vivo imaging; drug delivery

Funding

  1. China Postdoctoral Science Foundation [2013M540260]
  2. National Natural Science Foundation of China [91227118, 21104075]

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Near-infrared fluorescent nanovesides were prepared by self-assembly of block copolymer hydrophilic poly(ethylene glycol) boron-dipyrromethenes in aqueous solution. The fluorescence enhancement induced by dissociation of nanovesides could be used as a smart imaging and diagnostic tool. This nanovesicle could encapsulate the antitumor drug, and provide a powerful platform for imaging-guided tumor-specific drug delivery and therapy.

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