Related references
Note: Only part of the references are listed.Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity
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Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9
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Tim-3 expression and function in natural killer cells from metastatic melanoma patients
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IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma
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JOURNAL OF CLINICAL INVESTIGATION (2012)
TIM-3 Expression Characterizes Regulatory T Cells in Tumor Tissues and Is Associated with Lung Cancer Progression
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Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
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T-bet, a Th1 transcription factor regulates the expression of Tim-3
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Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion
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Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients
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Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
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T cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates natural killer cell suppression in chronic hepatitis B
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Tim-3/Galectin-9 Pathway: Regulation of Th1 Immunity through Promotion of CD11b+Ly-6G+ Myeloid Cells
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JOURNAL OF IMMUNOLOGY (2010)
Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells
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SCIENCE (2007)
TIM-1 and TIM-3 enhancement of Th2 cytokine poduction by mast cells
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BLOOD (2007)
Preferential involvement of Tim-3 in the regulation of hepatic CD8+ T cells in murine acute graft-versus-host disease
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JOURNAL OF IMMUNOLOGY (2006)
Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity
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JOURNAL OF IMMUNOLOGY (2006)
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
C Zhu et al.
NATURE IMMUNOLOGY (2005)
Immunosuppressive networks in the tumour environment and their therapeutic relevance
WP Zou
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Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance
A Sanchez-Fueyo et al.
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Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
L Monney et al.
NATURE (2002)
Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family
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