Journal
ACS APPLIED MATERIALS & INTERFACES
Volume 3, Issue 5, Pages 1740-1748Publisher
AMER CHEMICAL SOC
DOI: 10.1021/am200241b
Keywords
PEO grafting; protein resistance; non-fouling properties; collision-induced cross-linking; butyl rubber; coatings
Funding
- LANXESS Inc.
- Ontario Centres of Excellence
- Natural Sciences and Engineering Research Council of Canada
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The functionalization of surfaces with poly(ethylene oxide) (PEO) is an effective means of imparting resistance to the adsorption of proteins and the attachment and growth of cells, properties that are critical for many biomedical applications. In this work, a new hyperthermal hydrogen induced cross-linking (HHIC) method was explored as a simple one-step approach for attaching PEO to surfaces through the selective cleavage of C-H bonds and subsequent cross-linking of the resulting carbon radicals. In order to study the effects of the process on the polymer, PEO-coated silicon wafers were prepared and the effects of different treatment times were investigated. Subsequently, using an optimized treatment time and a modified butyl polymer with increased affinity for PEO, the technique was applied to butyl rubber surfaces. All of the treated surfaces exhibited significantly reduced protein adsorption and cell growth relative to control surfaces and compared favorably with surfaces that were functionalized with PEO using conventional chemical methods. Thus HHIC is a simple and effective means of attaching PEO to non-functional polymer surfaces.
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