Journal
ACS APPLIED MATERIALS & INTERFACES
Volume 1, Issue 2, Pages 232-234Publisher
AMER CHEMICAL SOC
DOI: 10.1021/am800093d
Keywords
polyfluorene; biosensor; alpha-amino acids; indirect strategy
Funding
- National Science Foundation of China [20674059]
- National Fundamental Key Research Program
- Hubei Province
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For the First time, a conjugated fluorescent polymer was utilized to probe alpha-amino acids, sensitively and selectively, through a new approach. First the strong fluorescence of the prepared polyfluorene (P1) was quenched by trace copper ions, and then the quenched fluorescence was recovered upon the addition of alpha-amino acids, making P1 a new and sensitive biosensor toward alpha-amino acids. The experimental results demonstrated that the alpha-amino acid selective nature of P1 over other analytes was relatively good. Thus, the work reported here might open up a new avenue for developing new biosensors.
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