4.8 Editorial Material

Kruppel-ling of IRF4-Dependent DCs into Two Functionally Distinct DC Subsets

Journal

IMMUNITY
Volume 42, Issue 5, Pages 785-787

Publisher

CELL PRESS
DOI: 10.1016/j.immuni.2015.04.020

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IRF4-dependent DCs have been associated with induction of both Th1 and Th17 cells. In this issue of Immunity, Tussiwand et al. (2015) demonstrate that a dependence on KLF4 identifies a subset of IRF4-dependent DC that preferentially promotes Th2 cell differentiation.

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