Related references
Note: Only part of the references are listed.Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection
Yutao Wang et al.
IMMUNITY (2017)
cGAS surveillance of micronuclei links genome instability to innate immunity
Karen J. Mackenzie et al.
NATURE (2017)
cGAS is essential for the antitumor effect of immune checkpoint blockade
Hua Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
cGAS is essential for cellular senescence
Hui Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes
Jessica F. Almine et al.
NATURE COMMUNICATIONS (2017)
SENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing
Ye Cui et al.
PLOS PATHOGENS (2017)
The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response
Qiang Wang et al.
PLOS PATHOGENS (2017)
Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection
Sebastian Aguirre et al.
NATURE MICROBIOLOGY (2017)
The cGAS-STING Defense Pathway and Its Counteraction by Viruses
Zhe Ma et al.
CELL HOST & MICROBE (2016)
Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus
Ming-Ming Hu et al.
IMMUNITY (2016)
RNase H2 catalytic core Aicardi-Goutieres syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice
Vladislav Pokatayev et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
TRIM14 Inhibits cGAS Degradation Mediated by Selective Autophagy Receptor p62 to Promote Innate Immune Responses
Meixin Chen et al.
MOLECULAR CELL (2016)
Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing
Qi Chen et al.
NATURE IMMUNOLOGY (2016)
Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity
Pengyan Xia et al.
NATURE IMMUNOLOGY (2016)
Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS
Guigen Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1
Sunnie M. Yoh et al.
CELL (2015)
Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein
Jian-jun Wu et al.
CELL HOST & MICROBE (2015)
Positive Feedback Regulation of Type I IFN Production by the IFN-Inducible DNA Sensor cGAS
Feng Ma et al.
JOURNAL OF IMMUNOLOGY (2015)
Mitochondrial DNA stress primes the antiviral innate immune response
A. Phillip West et al.
NATURE (2015)
Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA
Anna-Maria Herzner et al.
NATURE IMMUNOLOGY (2015)
Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
Daxing Gao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses
Zhe Ma et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection
Megan H. Orzalli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway
Laura Lau et al.
SCIENCE (2015)
Akt Kinase-Mediated Checkpoint of cGAS DNA Sensing Pathway
Gil Ju Seo et al.
CELL REPORTS (2015)
Cellular Sensing of Viral DNA and Viral Evasion Mechanisms
Megan H. Orzalli et al.
ANNUAL REVIEW OF MICROBIOLOGY, VOL 68 (2014)
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
Philip J. Kranzusch et al.
CELL (2014)
Crosstalk between the cGAS DNA Sensor and Beclin-1 Autophagy Protein Shapes Innate Antimicrobial Immune Responses
Qiming Liang et al.
CELL HOST & MICROBE (2014)
MITA/STING: A central and multifaceted mediator in innate immune response
Yong Ran et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2014)
Cytosolic RNA:DNA hybrids activate the cGAS-STING axis
Arun K. Mankan et al.
EMBO JOURNAL (2014)
Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway
Kathrine Hansen et al.
EMBO JOURNAL (2014)
The E3 Ubiquitin Ligase AMFR and INSIG1 Bridge the Activation of TBK1 Kinase by Modifying the Adaptor STING
Qiang Wang et al.
IMMUNITY (2014)
NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING
Lu Zhang et al.
IMMUNITY (2014)
The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling
Xin Cai et al.
MOLECULAR CELL (2014)
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
John W. Schoggins et al.
NATURE (2014)
Activated STING in a Vascular and Pulmonary Syndrome
Y. Liu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation
Maria Kalamvoki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization
Xin Li et al.
IMMUNITY (2013)
Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity
Qiang Ding et al.
JOURNAL OF HEPATOLOGY (2013)
Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
Xu Zhang et al.
MOLECULAR CELL (2013)
Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
Jiaxi Wu et al.
SCIENCE (2013)
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
Lijun Sun et al.
SCIENCE (2013)
Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses
Daxing Gao et al.
SCIENCE (2013)
TRIM32 Protein Modulates Type I Interferon Induction and Cellular Antiviral Response by Targeting MITA/STING Protein for K63-linked Ubiquitination
Jing Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response
Kislay Parvatiyar et al.
NATURE IMMUNOLOGY (2012)
Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity
Chia-Yi Yu et al.
PLOS PATHOGENS (2012)
DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING
Sebastian Aguirre et al.
PLOS PATHOGENS (2012)
Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
Greta Guarda et al.
IMMUNITY (2011)
A Family of Protein-Deglutamylating Enzymes Associated with Neurodegeneration
Krzysztof Rogowski et al.
CELL (2010)
Pattern Recognition Receptors and Inflammation
Osamu Takeuchi et al.
CELL (2010)
The Ubiquitin Ligase TRIM56 Regulates Innate Immune Responses to Intracellular Double-Stranded DNA
Tetsuo Tsuchida et al.
IMMUNITY (2010)
IFI16 is an innate immune sensor for intracellular DNA
Leonie Unterholzner et al.
NATURE IMMUNOLOGY (2010)
RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway
Yu-Hsin Chiu et al.
CELL (2009)
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
Teresa Fernandes-Alnemri et al.
NATURE (2009)
Ubiquitylation in innate and adaptive immunity
Vijay G. Bhoj et al.
NATURE (2009)
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
Veit Hornung et al.
NATURE (2009)
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
Tatsuya Saitoh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
Bo Zhong et al.
IMMUNITY (2008)
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
Hiroki Ishikawa et al.
NATURE (2008)
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
Akinori Takaoka et al.
NATURE (2007)
Share Paper
