Related references
Note: Only part of the references are listed.Potent EMT and CSC Phenotypes Are Induced By Oncostatin-M in Pancreatic Cancer
Jacob M. Smigiel et al.
MOLECULAR CANCER RESEARCH (2017)
FAM83 family oncogenes are broadly involved in human cancers: an integrative multi-omics approach
Antoine M. Snijders et al.
MOLECULAR ONCOLOGY (2017)
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
Angela M. Krebs et al.
NATURE CELL BIOLOGY (2017)
Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling
D. J. Junk et al.
ONCOGENE (2017)
High Expression of FAM83B Predicts Poor Prognosis in Patients with Pancreatic Ductal Adenocarcinoma and Correlates with Cell Cycle and Cell Proliferation
Chao-qin Shen et al.
JOURNAL OF CANCER (2017)
FAM83A is amplified and promotes cancer stem cell-like traits and chemoresistance in pancreatic cancer
S. Chen et al.
ONCOGENESIS (2017)
nab-Paclitaxel for the treatment of pancreatic cancer
George Kim
CANCER MANAGEMENT AND RESEARCH (2017)
MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer (vol 32, pg 71, 2017)
Surendra K. Shukla et al.
CANCER CELL (2017)
Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis
Jae-Seok Roe et al.
CELL (2017)
Employing Metabolism to Improve the Diagnosis and Treatment of Pancreatic Cancer
Christopher J. Habrook et al.
CANCER CELL (2017)
A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling
Sai Krishna Athuluri-Divakar et al.
CELL (2016)
Targeting focal adhesion kinase renders pancreatic cancers responsive to checkpoint immunotherapy
Hong Jiang et al.
NATURE MEDICINE (2016)
Pancreatic Cancer Epidemiology, Detection, and Management
Qiubo Zhang et al.
GASTROENTEROLOGY RESEARCH AND PRACTICE (2016)
Tumor-associated stromal cells as key contributors to the tumor microenvironment
Karen M. Bussard et al.
BREAST CANCER RESEARCH (2016)
T Cells Engineered against a Native Antigen Can Surmount Immunologic and Physical Barriers to Treat Pancreatic Ductal Adenocarcinoma
Ingunn M. Stromnes et al.
CANCER CELL (2015)
Clinical implications of epithelial cell plasticity in cancer progression
Luis A. Aparicio et al.
CANCER LETTERS (2015)
MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells
Patricia Sancho et al.
CELL METABOLISM (2015)
Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer
Clifford J. Whatcott et al.
CLINICAL CANCER RESEARCH (2015)
Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?
Adrienne D. Cox et al.
CLINICAL CANCER RESEARCH (2015)
Suppression of cancer relapse and metastasis by inhibiting cancer stemness
Youzhi Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Concise Review: Targeting Cancer Stem Cells Using Immunologic Approaches
Qin Pan et al.
STEM CELLS (2015)
Epithelial-Mesenchymal Plasticity: A Central Regulator of Cancer Progression
Xin Ye et al.
TRENDS IN CELL BIOLOGY (2015)
Aspirin counteracts cancer stem cell features, desmoplasia and gemcitabine resistance in pancreatic cancer
Yiyao Zhang et al.
ONCOTARGET (2015)
EMT, CTCs and CSCs in tumor relapse and drug-resistance
Abhisek Mitra et al.
ONCOTARGET (2015)
Pancreatic cancer and FOLFIRINOX: a new era and new questions
Robert De W. Marsh et al.
CANCER MEDICINE (2015)
PI3K/mTOR Dual Inhibitor VS-5584 Preferentially Targets Cancer Stem Cells
Vihren N. Kolev et al.
CANCER RESEARCH (2015)
JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells
Shuhei Suzuki et al.
ONCOTARGET (2015)
Targeting RAS-mutant Cancers: Is ERK the Key?
Meagan B. Ryan et al.
TRENDS IN CANCER (2015)
Therapeutic targeting of the oncostatin M receptor-β prevents inflammatory heart failure
Jochen Poeling et al.
BASIC RESEARCH IN CARDIOLOGY (2014)
The stromal compartments in pancreatic cancer: Are there any therapeutic targets?
Serena Lunardi et al.
CANCER LETTERS (2014)
Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
Lola Rahib et al.
CANCER RESEARCH (2014)
Molecular Pathways: Adaptive Kinome Reprogramming in Response to Targeted Inhibition of the BRAF-MEK-ERK Pathway in Cancer
Gary L. Johnson et al.
CLINICAL CANCER RESEARCH (2014)
Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α
Romain Baer et al.
GENES & DEVELOPMENT (2014)
Updated survival from a randomized phase III trial (MPACT) of nab-paclitaxel plus gemcitabine versus gemcitabine alone for patients (pts) with metastatic adenocarcinoma of the pancreas
David Goldstein et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Conserved Oncogenic Behavior of the FAM83 Family Regulates MAPK Signaling in Human Cancer
Rocky Cipriano et al.
MOLECULAR CANCER RESEARCH (2014)
Synergistic Activities of MET/RON Inhibitor BMS-777607 and mTOR Inhibitor AZD8055 to Polyploid Cells Derived from Pancreatic Cancer and Cancer Stem Cells
Jun-Ying Zeng et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
Andrea Viale et al.
NATURE (2014)
Serum Cytokine Profile in Patients With Pancreatic Cancer
Carolina Torres et al.
PANCREAS (2014)
A rapid nested polymerase chain reaction method to detect circulating cancer cells in breast cancer patients using multiple marker genes
Lei Liu et al.
ONCOLOGY LETTERS (2014)
Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer
Stefan Eser et al.
CANCER CELL (2013)
Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity
Christine L. Chaffer et al.
CELL (2013)
Pancreatic cancer: A comprehensive review and update
Thiruvengadam Muniraj et al.
DM DISEASE-A-MONTH (2013)
Roles for KRAS in Pancreatic Tumor Development and Progression
Marina Pasca di Magliano et al.
GASTROENTEROLOGY (2013)
Epithelial-mesenchymal plasticity in carcinoma metastasis
Jeff H. Tsai et al.
GENES & DEVELOPMENT (2013)
Addition of Algenpantucel-L Immunotherapy to Standard Adjuvant Therapy for Pancreatic Cancer: a Phase 2 Study
Jeffrey M. Hardacre et al.
JOURNAL OF GASTROINTESTINAL SURGERY (2013)
Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling
Gunther Zimmermann et al.
NATURE (2013)
Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine
Daniel D. Von Hoff et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Increased B Cell-Activating Factor Promotes Tumor Invasion and Metastasis in Human Pancreatic Cancer
Mitsuhito Koizumi et al.
PLOS ONE (2013)
Metformin Targets the Metabolic Achilles Heel of Human Pancreatic Cancer Stem Cells
Enza Lonardo et al.
PLOS ONE (2013)
Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling
Altaf Mohammed et al.
TRANSLATIONAL ONCOLOGY (2013)
Safety, tolerability, pharmacokinetics and pharmacodynamics of an anti- oncostatin M monoclonal antibody in rheumatoid arthritis: results from phase II randomized, placebo-controlled trials
Ernest H. Choy et al.
ARTHRITIS RESEARCH & THERAPY (2013)
mTOR plays critical roles in pancreatic cancer stem cells through specific and stemness-related functions
Shyuichiro Matsubara et al.
SCIENTIFIC REPORTS (2013)
Alteration of pancreatic cancer cell functions by tumor-stromal cell interaction
Shin Hamada et al.
FRONTIERS IN PHYSIOLOGY (2013)
Tumor Microenvironmental Signaling Elicits Epithelial-Mesenchymal Plasticity through Cooperation with Transforming Genetic Events
Damian J. Junk et al.
NEOPLASIA (2013)
Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells
Shin Hamada et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Mesenchymal and stemness circulating tumor cells in early breast cancer diagnosis
Guislaine Barriere et al.
BMC CANCER (2012)
Metformin Inhibits Cell Proliferation, Migration and Invasion by Attenuating CSC Function Mediated by Deregulating miRNAs in Pancreatic Cancer Cells
Bin Bao et al.
CANCER PREVENTION RESEARCH (2012)
Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells
Eleftherios Sachlos et al.
CELL (2012)
Understanding Metastasis in Pancreatic Cancer: A Call for New Clinical Approaches
David A. Tuveson et al.
CELL (2012)
Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness
Enza Lonardo et al.
CELL CYCLE (2012)
Cancer Stem Cells: Current Status and Evolving Complexities
Jane E. Visvader et al.
CELL STEM CELL (2012)
FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice
Sun-Young Lee et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
FAM83B mediates EGFR- and RAS-driven oncogenic transformation
Rocky Cipriano et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues
Michaela Aichler et al.
JOURNAL OF PATHOLOGY (2012)
Hypoxia-Induced Aggressiveness of Pancreatic Cancer Cells Is Due to Increased Expression of VEGF, IL-6 and miR-21, Which Can Be Attenuated by CDF Treatment
Bin Bao et al.
PLOS ONE (2012)
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
Till Maurer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A Lethally Irradiated Allogeneic Granulocyte-Macrophage Colony Stimulating Factor-Secreting Tumor Vaccine for Pancreatic Adenocarcinoma: A Phase II Trial of Safety, Efficacy, and Immune Activation
Eric Lutz et al.
ANNALS OF SURGERY (2011)
被撤回的出版物: Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells (Retracted article. See vol. 423, pg. 153, 2018)
Bin Bao et al.
CANCER LETTERS (2011)
Combination of salinomycin and gemcitabine eliminates pancreatic cancer cells
Guan-Nan Zhang et al.
CANCER LETTERS (2011)
c-Met Is a Marker of Pancreatic Cancer Stem Cells and Therapeutic Target
Chenwei Li et al.
GASTROENTEROLOGY (2011)
Hypoxia Induces Tumor Aggressiveness and the Expansion of CD133-Positive Cells in a Hypoxia-Inducible Factor-1 alpha-Dependent Manner in Pancreatic Cancer Cells
Okito Hashimoto et al.
PATHOBIOLOGY (2011)
Resveratrol Inhibits Pancreatic Cancer Stem Cell Characteristics in Human and KrasG12D Transgenic Mice by Inhibiting Pluripotency Maintaining Factors and Epithelial-Mesenchymal Transition
Sharmila Shankar et al.
PLOS ONE (2011)
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
Christine L. Chaffer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Synergistic Activity of Sorafenib and Sulforaphane Abolishes Pancreatic Cancer Stem Cell Characteristics
Vanessa Rausch et al.
CANCER RESEARCH (2010)
Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content
Salvatore Pece et al.
CELL (2010)
The therapeutic promise of the cancer stem cell concept
Natasha Y. Frank et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
TWISTing an embryonic transcription factor into an oncoprotein
S. Ansieau et al.
ONCOGENE (2010)
EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
A. Singh et al.
ONCOGENE (2010)
Sustained Src Inhibition Results in Signal Transducer and Activator of Transcription 3 (STAT3) Activation and Cancer Cell Survival via Altered Janus-Activated Kinase-STAT3 Binding
Banibrata Sen et al.
CANCER RESEARCH (2009)
Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature
Emmanuelle Charafe-Jauffret et al.
CANCER RESEARCH (2009)
Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
Piyush B. Gupta et al.
CELL (2009)
Side population of pancreatic cancer cells predominates in TGF-β-mediated epithelial to mesenchymal transition and invasion
Ayano Kabashima et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells
Sung Pil Hong et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation
G. Solinas et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
Kenneth P. Olive et al.
SCIENCE (2009)
Pancreatic cancer
Anirban Maitra et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2008)
Detection of circulating cancer cells in lung cancer patients with a panel of marker genes
Lei Liu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Significance of CD90+ cancer stem cells in human liver cancer
Zhen Fan Yang et al.
CANCER CELL (2008)
Pancreatic stellate cells and pancreatic cancer cells: An unholy alliance
Alain Vonlaufen et al.
CANCER RESEARCH (2008)
Cancer-associated stroma fibroblasts promote pancreatic tumor progression
Rosa F. Hwang et al.
CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
Hypoxia-inducible factor-1α regulates matrix metalloproteinase-1 activity in human bone marrow-derived mesenchymal stem cells
Jiunn-Liang Lin et al.
FEBS LETTERS (2008)
Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition
Anne-Pierre Morel et al.
PLOS ONE (2008)
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
Patrick C. Hermann et al.
CELL STEM CELL (2007)
Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes
Tan A. Ince et al.
CANCER CELL (2007)
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada clinical trials group
Malcolm J. Moore et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Identification of pancreatic cancer stem cells
Chenwei Li et al.
CANCER RESEARCH (2007)
Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition
Terence K. Lee et al.
CLINICAL CANCER RESEARCH (2006)
Drug penetration in solid tumours
Andrew I. Minchinton et al.
NATURE REVIEWS CANCER (2006)
Targeting multidrug resistance in cancer
G Szakács et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Prospective identification of tumorigenic prostate cancer stem cells
AT Collins et al.
CANCER RESEARCH (2005)
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
A Eger et al.
ONCOGENE (2005)
Isolation of cancer stem cells from adult glioblastoma multiforme
XP Yuan et al.
ONCOGENE (2004)
Gemcitabine and ISIS-2503 for patients with locally advanced or metastatic pancreatic adenocarcinoma: A north central cancer treatment group phase II trial
SR Alberts et al.
JOURNAL OF CLINICAL ONCOLOGY (2004)
Prospective identification of tumorigenic breast cancer cells
M Al-Hajj et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Targeting ras signalling pathways in cancer therapy
J Downward
NATURE REVIEWS CANCER (2003)
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
GL Johnson et al.
SCIENCE (2002)
Stem cells, cancer, and cancer stem cells
T Reya et al.
NATURE (2001)
Novel allogeneic granulocyte-macrophage colony-stimulating factor-secreting tumor vaccine for pancreatic cancer: A phase I trial of safety and immune activation
EM Jaffee et al.
JOURNAL OF CLINICAL ONCOLOGY (2001)
The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells
E Batlle et al.
NATURE CELL BIOLOGY (2000)