Journal
CHINESE JOURNAL OF CATALYSIS
Volume 32, Issue 9, Pages 1484-1489Publisher
SCIENCE PRESS
DOI: 10.1016/S1872-2067(10)60263-X
Keywords
dihydropyrimidinones; dihydropyrimidinthiones; ferroferric oxide nanoparticle; one-pot condensation; solvent-free
Funding
- Yasouj University Research Councils
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The catalytic activity of Fe3O4 nanoparticles (NPs) in a one-pot three component condensation reaction consisting of an aromatic aldehyde, urea or thiourea, and a beta-dicarbonyl under solvent-free conditions was investigated. This reaction affords the corresponding dihydropyrimidinones (thiones) in high to excellent yields. Compared with the classical Biginelli reactions this method consistently gives a high yield, easy magnetic separation, a short reaction time, and catalyst reusability.
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