4.4 Article

Simple Synthetic Method for the Functionalized Benzo[c]cinnolines

Journal

CHEMISTRYSELECT
Volume 3, Issue 7, Pages 2092-2095

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/slct.201800278

Keywords

azo compounds; benzo[c]cinnoline; 2,2 '-diamino-1,1 '-biaryls; nitrite; nitrogen heterocycles

Funding

  1. Chung-Ang University
  2. National Research Foundation of Korea [NRF-2017R1 A2B2004082]

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Functionalized benzo[c]cinnoline derivatives were synthesized from easily accessible 2,2-diamino-1,1'-biaryls using a nitrite source. In this simple process, various functional groups were tolerated under mild reaction conditions, and the practicality of the process was demonstrated through the gram-scale production of the benzo[c]cinnolines.

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