Environmentally Benign Deep Eutectic Solvent for Synthesis of 1,3-Thiazolidin-4-ones

This paper explores the versatility and effectiveness of Deep Eutectic Solvent (DES) as an efficient catalyst cum reaction media for the preparation of biologically important 1,3- thiazolidin-4-one derivatives. This methodology was objected to overcome the limitations of the previously reported methods such as the use of expensive and toxic solvents, long reaction time and low yield. This protocol is rapid, environmentally benign, with good to high yield of products. The DES media could be reused up to five times without any appreciable decrease in the yield.