Journal
ANNALS OF CLINICAL BIOCHEMISTRY
Volume 56, Issue 1, Pages 7-14Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/0004563218774816
Keywords
Iodine; thyroid disease; epidemiology studies
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Iodine deficiency is a significant global health concern, and the single greatest cause of preventable cognitive impairment. It is also a growing public health concern in the UK particularly among pregnant women. Biomarkers such as urinary iodine concentration have clear utility in epidemiological studies to investigate population-level iodine status, but determination of iodine status in individuals is much more problematic with current assays. This article reviews the available biomarkers of iodine status and their relative utility at the level of both populations and individuals for the investigation of iodine deficiency and iodine excess.
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