Journal
CANCER MANAGEMENT AND RESEARCH
Volume 10, Issue -, Pages 199-206Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/CMAR.S153482
Keywords
colorectal cancer; bacteria; microbiology; carbohydrate metabolism; lipid metabolism; amino acids; inflammation
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Colorectal cancer is one of the most common human malignant tumors. Recent research has shown that colorectal cancer is a dysbacteriosis-induced disease; however, the role of intestinal bacteria in colorectal cancer is unclear. This review explores the role of intestinal flora in colorectal cancer. In total, 57 articles were included after identification and screening. The pertinent literature on floral metabolites in colorectal cancer from three metabolic perspectives - including carbohydrate, lipid, and amino acid metabolism - was analyzed. An association network regarding the role of intestinal flora from a metabolic perspective was constructed by analyzing the previous literature to provide direction and insight for further research on intestinal flora in colorectal cancer.
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