4.5 Article

Draft genome sequence of Annulohypoxylon stygium, Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis basicola), Ceratocystis smalleyi, two Cercospora beticola strains, Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina, and Morchella septimelata

Journal

IMA FUNGUS
Volume 9, Issue 1, Pages 199-223

Publisher

BMC
DOI: 10.5598/imafungus.2018.09.01.13

Keywords

Beta vulgaris; Carya cordiformis; echinocandin gene clusters; mulundocandins; Pitch canker; peumocandins

Categories

Funding

  1. University of Pretoria
  2. Tree Protection Co-operative Programme (TPCP)
  3. DST-NRF Centre of Excellence in Tree Health Biotechnology
  4. National Research Foundation
  5. Genomics Research Institute (GRI)
  6. DST-NRF SARCHI chair on Fungal Genomics
  7. United States Department of Agriculture
  8. National Institute of Food and Agriculture Hatch project [NYG-625424]
  9. Director's Controlled Endowment Fund of The New York Agricultural Experiment Station, Cornell University, Geneva, New York, USA
  10. National Natural Science Foundation of China (NSFC) [31629001, 31741004]
  11. Welch Foundation [AU-0042-20030616]
  12. Kay and Ben Fortson Endowment

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Draft genomes of the species Annulohypoxylon stygium, Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis basicola), Ceratocystis smalleyi, two Cercospora beticola strains, Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf hyalina and Morchella septimelata are presented. Both mating types (MAT1-1 and MAT1-2) of Cercospora beticola are included. Two strains of Coleophoma cylindrospora that produce sulfated homotyrosine echinocandin variants, FR209602, FR220897 and FR220899 are presented. The sequencing of Aspergillus mulundensis, Coleophoma cylindrospora and Phialophora cf. hyalina has enabled mapping of the gene clusters encoding the chemical diversity from the echinocandin pathways, providing data that reveals the complexity of secondary metabolism in these different species. Overall these genomes provide a valuable resource for understanding the molecular processes underlying pathogenicity (in some cases), biology and toxin production of these economically important fungi.

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