4.7 Article

Silver-catalyzed ring-opening difluoromethylthiolation/trifluoromethylthiolation of cycloalkanols with PhSO2SCF2H or PhSO2SCF3

Journal

ORGANIC CHEMISTRY FRONTIERS
Volume 5, Issue 9, Pages 1462-1465

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8qo00115d

Keywords

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Funding

  1. National Natural Science Foundation of China [21625206, 21632009, 21572258, 21421002]
  2. Strategic Priority Research Program of the Chinese Academy of Sciences [XDB20000000]

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A silver-catalyzed ring-opening difluoromethylthiolation/trifluoromethylthiolation of cycloalkanols including cyclopropanols, cyclobutanols, cyclopentanols, cyclohexanols and cycloheptanols was described. A variety of common functional groups such as fluoride, chloride, bromide, iodide, trifluoromethyl, cyano and ester groups were compatible.

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