Journal
OPEN CHEMISTRY
Volume 16, Issue 1, Pages 349-361Publisher
DE GRUYTER POLAND SP ZOO
DOI: 10.1515/chem-2018-0040
Keywords
p-menth-1-en-8-ol; monoterpene utilization; monoterpenoid alcohol; monocyclic monoterpenoids; terpenic alcohols
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Terpineols are monocyclic monoterpene tertiary alcohols which are naturally present in plant species. There are five common isomers of terpineols, alpha-, beta-, gamma-, delta-and terpinen-4-ol, of which alpha-terpineol and its isomer terpinen-4-ol are the most common terpineols found in nature. alpha-Terpineol plays an important role in the industrial field. It has a pleasant odor similar to lilacs and it is a common ingredient in perfumes, cosmetics, and aromatic scents. In addition, alpha-terpineol attracts a great interest as it has a wide range of biological applications as an antioxidant, anticancer, anticonvulsant, antiulcer, antihypertensive, anti-nociceptive compound. It is also used to enhance skin penetration, and also has insecticidal properties. This study reviews the relevance of alpha-terpineol based on scientific findings on Google Scholar, Pubmed, Web of Science, Scopus and Chemical Abstracts. Collectively, the use of alpha-terpineol in medicine and in the pharmaceutical industry plays an important role in therapeutic applications. This review will, therefore, support future research in the utilization of alpha-terpineol.
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