Journal
JOURNAL OF STROKE
Volume 20, Issue 2, Pages 208-+Publisher
KOREAN STROKE SOC
DOI: 10.5853/jos.2018.00150
Keywords
Ischemic stroke; Atherosclerosis; Intracranial; Stenosis; Magnetic resonance imaging
Categories
Funding
- Korea Health Technology RD project [HC15C1056]
- National Research Foundation of Korea [2018R1A2B2003489]
- Intramural Research Fund for Cardiovascular Diseases of the National Cerebral and Cardiovascular Center, Japan [H28-4-1]
- Ministry for Health, Welfare and Family Affairs, Korea [HI14C1985]
- National Research Foundation of Korea [2018R1A2B2003489] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Intracranial large artery disease (ILAD) is the major cause of stroke worldwide. With the application of recently introduced diagnostic techniques, the prevalence of non-atherosclerotic ILAD is expected to increase. Herein, we reviewed recent reports and summarized progress in the diagnosis and clinical impact of differentiation between ILAD of atherosclerotic and non-atherosclerotic origin. Our review of the literature suggests that more careful consideration of non-atherosclerotic causes and the application of appropriate diagnostic techniques in patients with ILAD may not only provide better results in the treatment of patients, but it may also lead to more successful clinical trials for the treatment of intracranial atherosclerosis.
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