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BIOCHEMICAL SOCIETY TRANSACTIONS (2013)
Cerebrospinal-fluid cytokine and chemokine profile in patients with pneumococcal and meningococcal meningitis
Leonam G. Coutinho et al.
BMC INFECTIOUS DISEASES (2013)
Expression of CXCR3 and its ligands CXCL9,-10 and-11 in paediatric opsoclonusmyoclonus syndrome
M. R. Pranzatelli et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2013)
Diagnostic Value of Cytokines and Chemokines in Lyme Neuroborreliosis
T. Cerar et al.
CLINICAL AND VACCINE IMMUNOLOGY (2013)
A review of phase II trial designs for initial marker validation
Sumithra J. Mandrekar et al.
CONTEMPORARY CLINICAL TRIALS (2013)
Neuron-Microglia Interaction in Neuroinflammation
Akio Suzumura
CURRENT PROTEIN & PEPTIDE SCIENCE (2013)
Emerging role of interleukin-22 in autoimmune diseases
Hai-Feng Pan et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2013)
The Interleukin-1 Family: Back to the Future
Cecilia Garlanda et al.
IMMUNITY (2013)
Virus infection, antiviral immunity, and autoimmunity
Daniel R. Getts et al.
IMMUNOLOGICAL REVIEWS (2013)
Neutralizing Nanobodies Targeting Diverse Chemokines Effectively Inhibit Chemokine Function
Christophe Blanchetot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Pediatric Reference Ranges for Proinflammatory and Anti-Inflammatory Cytokines in Cerebrospinal Fluid and Serum by Multiplexed Immunoassay
Michael R. Pranzatelli et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2013)
Characterization of natural killer cells in paired CSF and blood samples during neuroinflammation
Isabell Hamann et al.
JOURNAL OF NEUROIMMUNOLOGY (2013)
BAFF/APRIL system in pediatric OMS: relation to severity, neuroinflammation, and immunotherapy
Michael R. Pranzatelli et al.
JOURNAL OF NEUROINFLAMMATION (2013)
Cytokines, cytokine antagonists, and soluble adhesion molecules in pediatric OMS and other neuroinflammatory disorders
Michael R. Pranzatelli et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2013)
CXCL13 is a biomarker of inflammation in multiple sclerosis, neuromyelitis optica, and other neurological conditions
Enrique Alvarez et al.
MULTIPLE SCLEROSIS JOURNAL (2013)
The Causative Pathogen Determines the Inflammatory Profile in Cerebrospinal Fluid and Outcome in Patients with Bacterial Meningitis
Denis Grandgirard et al.
MEDIATORS OF INFLAMMATION (2013)
Elevation of proinflammatory cytokines in patients with Aicardi-Goutieres syndrome
Asako Takanohashi et al.
NEUROLOGY (2013)
A Role for the CXCR3/CXCL10 Axis in Rasmussen Encephalitis
Isabel Mirones et al.
PEDIATRIC NEUROLOGY (2013)
Feasibility of the Use of Combinatorial Chemokine Arrays to Study Blood and CSF in Multiple Sclerosis
Keith R. Edwards et al.
PLOS ONE (2013)
B-cell targeted therapeutics in clinical development
Stephan Blueml et al.
ARTHRITIS RESEARCH & THERAPY (2013)
Th1 and Th17 but no Th2-related cytokine spectrum in the cerebrospinal fluid of children with Borrelia-related facial nerve palsy
Zuzana Liba et al.
FLUIDS AND BARRIERS OF THE CNS (2013)
Daclizumab Use in Patients With Pediatric Multiple Sclerosis
Mark P. Gorman et al.
ARCHIVES OF NEUROLOGY (2012)
Cellular Immune Suppression in Paraneoplastic Neurologic Syndromes Targeting Intracellular Antigens
Dana Orange et al.
ARCHIVES OF NEUROLOGY (2012)
A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis
Michael Yellin et al.
ARTHRITIS AND RHEUMATISM (2012)
Pharmacological modulation of chemokine receptor function
D. J. Scholten et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Cerebrospinal Fluid IL-21 Levels in Neuromyelitis Optica and Multiple Sclerosis
Aimin Wu et al.
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES (2012)
Interleukin-1 receptor antagonist reverses stroke-associated peripheral immune suppression
Craig J. Smith et al.
CYTOKINE (2012)
Innate immunity in the central nervous system
Richard M. Ransohoff et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
CCR2+CCR5+ T Cells Produce Matrix Metalloproteinase-9 and Osteopontin in the Pathogenesis of Multiple Sclerosis
Wakiro Sato et al.
JOURNAL OF IMMUNOLOGY (2012)
A Phase III, Randomized, Controlled Trial of the Fully Human IL-12/23 mAb Briakinumab in Moderate-to-Severe Psoriasis
Kenneth B. Gordon et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
Key role of CXCL13/CXCR5 axis for cerebrospinal fluid B cell recruitment in pediatric OMS
Michael R. Pranzatelli et al.
JOURNAL OF NEUROIMMUNOLOGY (2012)
IL-17 and IL-22 in Cerebrospinal Fluid and Plasma Are Elevated in Guillain-Barre Syndrome
Shujuan Li et al.
MEDIATORS OF INFLAMMATION (2012)
Proinflammatory cytokines in serum and cerebrospinal fluid of CIDP patients
Michael Rentzos et al.
NEUROLOGICAL RESEARCH (2012)
Characterization of 99mTc-labeled cytokine ligands for inflammation imaging via TNF and IL-1 pathways
Zhonglin Liu et al.
NUCLEAR MEDICINE AND BIOLOGY (2012)
Elevated Cerebral Spinal Fluid Cytokine Levels in Boys with Cerebral Adrenoleukodystrophy Correlates with MRI Severity
Troy C. Lund et al.
PLOS ONE (2012)
Cerebrospinal Fluid IL-12p40, CXCL13 and IL-8 as a Combinatorial Biomarker of Active Intrathecal Inflammation
Bibiana Bielekova et al.
PLOS ONE (2012)
CXCL13 chemokine in pediatric and adult neuroborreliosis
N. Wutte et al.
ACTA NEUROLOGICA SCANDINAVICA (2011)
The blood-brain barrier, chemokines and multiple sclerosis
David W. Holman et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Increased levels of cytokines and high-mobility group box 1 are associated with the development of severe pneumonia, but not acute encephalopathy, in 2009 H1N1 influenza-infected children
Yoshinori Ito et al.
CYTOKINE (2011)
Probing cytokines, chemokines and matrix metalloproteinases towards better immunotherapies of multiple sclerosis
Ghislain Opdenakker et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2011)
Discriminating Lyme Neuroborreliosis from Other Neuroinflammatory Diseases by Levels of CXCL13 in Cerebrospinal Fluid
N. D. van Burgel et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2011)
GM-CSF-Based Fusion Cytokines as Ligands for Immune Modulation
Patrick Williams et al.
JOURNAL OF IMMUNOLOGY (2011)
Indications of Th1 and Th17 responses in cerebrospinal fluid from patients with Lyme neuroborreliosis: a large retrospective study
Anna J. Henningsson et al.
JOURNAL OF NEUROINFLAMMATION (2011)
A TNF Receptor 2 Selective Agonist Rescues Human Neurons from Oxidative Stress-Induced Cell Death
Roman Fischer et al.
PLOS ONE (2011)
Enhanced expression of cytokines/chemokines in cerebrospinal fluids in mumps meningitis in children
Takeshi Asano et al.
PEDIATRICS INTERNATIONAL (2011)
Monoclonal antibodies for the treatment of asthma
Matthew C. Catley et al.
PHARMACOLOGY & THERAPEUTICS (2011)
Canakinumab (ACZ885, a fully human IgG1 anti-IL-1 beta mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS)
Jasmin B. Kuemmerle-Deschner et al.
ARTHRITIS RESEARCH & THERAPY (2011)
Phase 2a Study of the CCR5 Monoclonal Antibody PRO 140 Administered Intravenously to HIV-Infected Adults
Jeffrey M. Jacobson et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Recombinant immunotherapeutics: current state and perspectives regarding the feasibility and market
Chung-Jr Huang et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)
Serum and cerebrospinal fluid cytokine concentrations in subacute sclerosing panencephalitis
Oemer Faruk Aydin et al.
BRAIN & DEVELOPMENT (2010)
GPCR signalling to the translation machinery
Astrid Musnier et al.
CELLULAR SIGNALLING (2010)
Mechanisms of injury in bacterial meningitis
Joachim Gerber et al.
CURRENT OPINION IN NEUROLOGY (2010)
CCR1 Antagonists: What Have We Learned From Clinical Trials
Ronald P. Gladue et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2010)
IL-17 is elevated in cerebrospinal fluids in bacterial meningitis in children
Takeshi Asano et al.
CYTOKINE (2010)
Natalizumab treatment in multiple sclerosis: marked decline of chemokines and cytokines in cerebrospinal fluid
J. Mellergard et al.
MULTIPLE SCLEROSIS JOURNAL (2010)
Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6
Akiyuki Uzawa et al.
MULTIPLE SCLEROSIS JOURNAL (2010)
Cytokines and chemokines in viral encephalitis: A clinicoradiological correlation
Jayantee Kalita et al.
NEUROSCIENCE LETTERS (2010)
The Chemokine CXCL13 Is a Prognostic Marker in Clinically Isolated Syndrome (CIS)
Johannes Brettschneider et al.
PLOS ONE (2010)
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Florent Ginhoux et al.
SCIENCE (2010)
Chemokines and chemokine receptors: new insights into cancer-related inflammation
Gwendal Lazennec et al.
TRENDS IN MOLECULAR MEDICINE (2010)
CCR5: From Natural Resistance to a New Anti-HIV Strategy
Lucia Lopalco
VIRUSES-BASEL (2010)
Serum sickness, encephalitis and other complications of anti-cytokine therapy
Severine Vermeire et al.
BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY (2009)
Engineered protein scaffolds as next-generation antibody therapeutics
Michaela Gebauer et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2009)
A substantial number of Rasmussen syndrome patients have increased IgG, CD4(+) T cells, TNF alpha, and Granzyme B in CSF
Yukitoshi Takahashi et al.
EPILEPSIA (2009)
Reduced levels of interleukin-1 receptor antagonist in the cerebrospinal fluid in patients with West syndrome
Kazuhiro Haginoya et al.
EPILEPSY RESEARCH (2009)
Chemokines and Chemokine Receptors: Standing at the Crossroads of Immunobiology and Neurobiology
Richard M. Ransohoff
IMMUNITY (2009)
Detection of MCP-1 and IL-8 in the serum and cerebrospinal fluid of a child with Miller Fisher syndrome
Satoshi Sato et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2009)
Selective Inhibition of CCR2 Expressing Lymphomyeloid Cells in Experimental Autoimmune Encephalomyelitis by a GM-CSF-MCP1 Fusokine
Moutih Rafei et al.
JOURNAL OF IMMUNOLOGY (2009)
Inhibition of CCR6 Function Reduces the Severity of Experimental Autoimmune Encephalomyelitis via Effects on the Priming Phase of the Immune Response
Adrian Liston et al.
JOURNAL OF IMMUNOLOGY (2009)
Elevated B-cell activating factor BAFF, but not APRIL, correlates with CSF cerebellar autoantibodies in pediatric opsoclonus-myoclonus syndrome
V. Fuehlhuber et al.
JOURNAL OF NEUROIMMUNOLOGY (2009)
Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS
F. Sellebjerg et al.
NEUROLOGY (2009)
An Autoinflammatory Disease with Deficiency of the Interleukin-1-Receptor Antagonist
Ivona Aksentijevich et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Interleukin-6 in neuro-Behcet's disease: Association with disease subsets and long-term outcome
Guelsen Akman-Demir et al.
CYTOKINE (2008)
Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in Aicardi-Goutieres syndrome
Jane T. van Heteren et al.
GLIA (2008)
A New Approach to the Blocking of Alloreactive T Cell-Mediated Graft-versus-Host Disease by In Vivo Administration of Anti-CXCR3 Neutralizing Antibody
Shan He et al.
JOURNAL OF IMMUNOLOGY (2008)
Lymphoid chemokines in chronic neuroinflammation
Francesca Aloisi et al.
JOURNAL OF NEUROIMMUNOLOGY (2008)
Sjogren's syndrome-associated meningoencephalomyelitis: Cerebrospinal fluid cytokine levels and therapeutic utility of tacrolimus
Takayuki Hoshina et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)
Repeated subcutaneous injections of IL12/23 P40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study
Benjamin M. Segal et al.
LANCET NEUROLOGY (2008)
Distinct CSF cytokine/chemokine profiles in atopic myelitis and other causes of myelitis
M. Tanaka et al.
NEUROLOGY (2008)
Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: Effects of moderate hypothermia
Sandra D. W. Buttram et al.
JOURNAL OF NEUROTRAUMA (2007)
APC-derived cytokines and T cell polarization in autoimmune inflammation
Ilona Gutcher et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Interleukin-6 and chemokines in the neuropsychiatric manifestations of systemic lupus erythematosus
H. Fragoso-Loyo et al.
ARTHRITIS AND RHEUMATISM (2007)
Cytokines and chemokines in cerebrospinal fluid and serum of adult patients with acute disseminated encephalomyelitis
Diego Franciotta et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2006)
Chemokine expression by astrocytes plays a role in microglia/macrophage activation and subsequent neurodegeneration in secondary progressive multiple sclerosis
Naoyuki Tanuma et al.
ACTA NEUROPATHOLOGICA (2006)
A randomized controlled trial with an anti-CCL2 (anti-monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritis
Jasper J. Haringman et al.
ARTHRITIS AND RHEUMATISM (2006)
Analysis of serum and cerebrospinal fluid cytokine levels in subacute sclerosing panencephalitis in Papua New Guinea
T Ichiyama et al.
CYTOKINE (2006)
CSF cytokine and chemokine profiles in acute disseminated encephalomyelitis
Takaaki Ishizu et al.
JOURNAL OF NEUROIMMUNOLOGY (2006)
Chemokine receptors as biomarkers in multiple sclerosis
Robert J. Fox et al.
DISEASE MARKERS (2006)
Chemokine blockers - therapeutics in the making?
TNC Wells et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
Cerebrospinal fluid interleukin-6 levels in patients with West syndrome
H Tekgul et al.
BRAIN & DEVELOPMENT (2006)
Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment
M Krumbholz et al.
BRAIN (2006)
Elevated interleukin-12 and CXCL10 in subacute sclerosing panencephalitis
G Saruhan-Direskeneli et al.
CYTOKINE (2005)
The chemokine CXCL13 (BLC): A putative diagnostic marker for neuroborreliosis
TA Rupprecht et al.
NEUROLOGY (2005)
Cytokines involved in CNS manifestations caused by Mycoplasma pneumoniae
M Narita et al.
PEDIATRIC NEUROLOGY (2005)
Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases
L Cartier et al.
BRAIN RESEARCH REVIEWS (2005)
BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma
M Krumbholz et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Expression of CCR7 in multiple sclerosis:: Implications for CNS immunity
P Kivisäkk et al.
ANNALS OF NEUROLOGY (2004)
Development of biomarkers in multiple sclerosis
B Bielekova et al.
BRAIN (2004)
Experience with immunomodulatory treatments in Rasmussen's encephalitis
T Granata et al.
NEUROLOGY (2003)
CSF and serum immune parameters in Sydenham's chorea: evidence of an autoimmune syndrome?
AJ Church et al.
JOURNAL OF NEUROIMMUNOLOGY (2003)
The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE)
DJ Mahad et al.
SEMINARS IN IMMUNOLOGY (2003)
International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on terms and symbols in quantitative pharmacology
RR Neubig et al.
PHARMACOLOGICAL REVIEWS (2003)
Interleukin-1β, tumor necrosis factor-α, and nitrite levels in febrile seizures
S Haspolat et al.
JOURNAL OF CHILD NEUROLOGY (2002)
Increased expression of the Th1-inducing cytokines interleukin-12 and interleukin-18 in cerebrospinal fluid but not in sera from patients with Lyme neuroborreliosis
M Grusell et al.
JOURNAL OF NEUROIMMUNOLOGY (2002)
T-cells in the cerebrospinal fluid express a similar repertoire of inflammatory chemokine receptors in the absence or presence of CNS inflammation:: implications for CNS trafficking
P Kivisäkk et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2002)
Multiple sclerosis and optic neuritis:: CCR5 and CXCR3 expressing T cells are augmented in blood and cerebrospinal fluid
N Teleshova et al.
JOURNAL OF NEUROLOGY (2002)
Recruitment of dendritic cells to the cerebrospinal fluid in bacterial neuroinfections
M Pashenkov et al.
JOURNAL OF NEUROIMMUNOLOGY (2002)
A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist
WF Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis
DR Huang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Virus-induced autoimmunity: Potential role of viruses in initiation, perpetuation, and progression of T-cell-mediated autoimmune disease
JK Olson et al.
VIRAL IMMUNOLOGY (2001)
Chemokines: A new classification system and their role in immunity
A Zlotnik et al.
IMMUNITY (2000)