Journal
EPILEPTIC DISORDERS
Volume 13, Issue 4, Pages 435-440Publisher
JOHN LIBBEY EUROTEXT LTD
DOI: 10.1684/epd.2011.0480
Keywords
brain stimulation; cortical mapping; mirth; laughter; language areas; negative motor areas; gelastic seizures
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There are few reports of laughter and/or mirth evoked by electrical stimulation of the brain. In this study, we present a patient with intractable epilepsy in whom mirth and laughter was consistently produced during stimulation of the left inferior frontal gyrus (opercular part) using stereotactically placed depth electrodes. A review of the literature shows that cortical sites that produce mirth when stimulated are located in the dominant hemisphere close to language areas or cortical negative motor areas.
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