Journal
JOURNAL OF THORACIC DISEASE
Volume 10, Issue -, Pages S112-S123Publisher
AME PUBL CO
DOI: 10.21037/jtd.2017.10.161
Keywords
Narcolepsy; hypersomnia; Kleine-Levin; sleep disorders
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The central hypersomnias encompass a range of conditions causing persisting or intermittent excessive daytime sleepiness (EDS). These conditions therefore present not infrequently in general clinical sleep practice, and remain in the differential for patients presenting with sleepiness. Our understanding of the pathophysiology, diagnosis and management of these conditions has progressed significantly over recent years, and in this article we review this group of disorders, focussing in particular on recent changes in classification and diagnosis, pathophysiological advances, and novel treatment options.
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