4.3 Review

Regulation of Immune Cell Functions by Metabolic Reprogramming

Related references

Note: Only part of the references are listed.
Review Hematology

Metabolic regulation of macrophages in tumor microenvironment

Jaehong Kim et al.

CURRENT OPINION IN HEMATOLOGY (2018)

Review Biochemistry & Molecular Biology

Non- metabolic functions of glycolytic enzymes in tumorigenesis

X. Yu et al.

ONCOGENE (2017)

Article Multidisciplinary Sciences

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity

Sydney R. Gordon et al.

NATURE (2017)

Review Immunology

Macrophage Metabolism As Therapeutic Target for Cancer, Atherosclerosis, and Obesity

Xenia Geeraerts et al.

FRONTIERS IN IMMUNOLOGY (2017)

Article Biochemistry & Molecular Biology

Redox regulation in metabolic programming and inflammation

Helen R. Griffiths et al.

REDOX BIOLOGY (2017)

Article Cell Biology

Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

Mathias Wenes et al.

CELL METABOLISM (2016)

Review Medicine, Research & Experimental

Metabolic regulation of immune responses: therapeutic opportunities

Nadine Assmann et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Immunology

The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease

Tsuyoshi Shirai et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2016)

Review Medicine, General & Internal

Liver innate immune cells and insulin resistance: the multiple facets of Kupffer cells

J. Jager et al.

JOURNAL OF INTERNAL MEDICINE (2016)

Article Cell Biology

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages

Jan Van den Bossche et al.

CELL REPORTS (2016)

Review Immunology

Pyruvate Kinase M2: A Potential Target for Regulating inflammation

Jose C. Alves-Filho et al.

FRONTIERS IN IMMUNOLOGY (2016)

Review Immunology

The Macrophage Switch in Obesity Development

Angela Castoldi et al.

FRONTIERS IN IMMUNOLOGY (2016)

Review Oncology

Metabolic communication in tumors: a new layer of immunoregulation for immune evasion

Ping-Chih Ho et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2016)

Article Multidisciplinary Sciences

Pyruvate Kinase M2 Activates mTORC1 by Phosphorylating AKT1S1

Chang-Liang He et al.

SCIENTIFIC REPORTS (2016)

Review Biochemistry & Molecular Biology

ROS homeostasis and metabolism: a critical liaison for cancer therapy

Jongdoo Kim et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2016)

Review Oncology

Clinical significance of T cell metabolic reprogramming in cancer

Christoph Herbel et al.

CLINICAL AND TRANSLATIONAL MEDICINE (2016)

Editorial Material Biochemistry & Molecular Biology

Nutrient Competition: A New Axis of Tumor Immunosuppression

Madhusudhanan Sukumar et al.

Article Biochemistry & Molecular Biology

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

Ping-Chih Ho et al.

Article Biochemistry & Molecular Biology

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

Chih-Hao Chang et al.

Review Biochemistry & Molecular Biology

T lymphocyte regulation by mevalonate metabolism

Martin Thurnher et al.

SCIENCE SIGNALING (2015)

Review Endocrinology & Metabolism

Metabolic Enzymes Enjoying New Partnerships as RNA-Binding Proteins

Alfredo Castello et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2015)

Article Multidisciplinary Sciences

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

Nikolaos Patsoukis et al.

NATURE COMMUNICATIONS (2015)

Review Biochemistry & Molecular Biology

T lymphocyte regulation by mevalonate metabolism

Martin Thurnher et al.

SCIENCE SIGNALING (2015)

Review Oncology

Tumors: Wounds That Do Not Heal-Redux

Harold F. Dvorak

CANCER IMMUNOLOGY RESEARCH (2015)

Article Multidisciplinary Sciences

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis

Jan Van den Bossche et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2015)

Review Immunology

Cellular Metabolism and Macrophage Functional Polarization

Linnan Zhu et al.

INTERNATIONAL REVIEWS OF IMMUNOLOGY (2015)

Article Multidisciplinary Sciences

Opposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression

Ang Yuan et al.

SCIENTIFIC REPORTS (2015)

Article Oncology

VDR Status Arbitrates the Prometastatic Effects of Tumor-Associated Macrophages

Yan Zhang et al.

MOLECULAR CANCER RESEARCH (2014)

Article Multidisciplinary Sciences

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

Oscar R. Colegio et al.

NATURE (2014)

Article Cell Biology

Metabolic control of YAP and TAZ by the mevalonate pathway

Giovanni Sorrentino et al.

NATURE CELL BIOLOGY (2014)

Article Immunology

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

Stanley Ching-Cheng Huang et al.

NATURE IMMUNOLOGY (2014)

Review Cell Biology

Metabolic requirements for the maintenance of self-renewing stem cells

Keisuke Ito et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Article Multidisciplinary Sciences

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity

Shih-Chin Cheng et al.

SCIENCE (2014)

Review Immunology

Molecular mechanisms that influence the macrophage M1-M2 polarization balance

Nan Wang et al.

FRONTIERS IN IMMUNOLOGY (2014)

Article Biochemistry & Molecular Biology

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

Chih-Hao Chang et al.

Review Multidisciplinary Sciences

Metabolism of inflammation limited by AMPK and pseudo-starvation

Luke A. J. O'Neill et al.

NATURE (2013)

Article Multidisciplinary Sciences

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

G. M. Tannahill et al.

NATURE (2013)

Article Multidisciplinary Sciences

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production

Alessandro Michelucci et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

Alfredo Castello et al.

Article Medicine, Research & Experimental

Macrophage plasticity and polarization: in vivo veritas

Antonio Sica et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

Article Biochemistry & Molecular Biology

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Dimitrios Anastasiou et al.

NATURE CHEMICAL BIOLOGY (2012)

Review Immunology

Differential macrophage programming in the tumor microenvironment

Brian Ruffell et al.

TRENDS IN IMMUNOLOGY (2012)

Article Biochemistry & Molecular Biology

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

Eric V. Dang et al.

Article Microbiology

Trained Immunity: A Memory for Innate Host Defense

Mihai G. Netea et al.

CELL HOST & MICROBE (2011)

Article Biochemistry & Molecular Biology

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

Daniel A. Winer et al.

NATURE MEDICINE (2011)

Review Biochemistry & Molecular Biology

Macrophage Diversity Enhances Tumor Progression and Metastasis

Bin-Zhi Qian et al.

Review Cardiac & Cardiovascular Systems

Control of Macrophage Activation and Function by PPARs

Ajay Chawla

CIRCULATION RESEARCH (2010)

Article Immunology

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

Juan-Carlos Rodriguez-Prados et al.

JOURNAL OF IMMUNOLOGY (2010)

Review Biochemistry & Molecular Biology

The REM phase of gene regulation

Matthias W. Hentze et al.

TRENDS IN BIOCHEMICAL SCIENCES (2010)

Article Cell Biology

Glycolytic control of adjuvant-induced macrophage survival: role of PI3K, MEK1/2, and Bcl-2

Margaret Chang et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Glycolytic Flux Signals to mTOR through Glyceraldehyde-3-Phosphate Dehydrogenase-Mediated Regulation of Rheb

Mi Nam Lee et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Multidisciplinary Sciences

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

Erika L. Pearce et al.

NATURE (2009)

Article Multidisciplinary Sciences

mTOR regulates memory CD8 T-cell differentiation

Koichi Araki et al.

NATURE (2009)

Article Multidisciplinary Sciences

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Carles Canto et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

Satoshi Nishimura et al.

NATURE MEDICINE (2009)

Article Multidisciplinary Sciences

mTOR and HIF-1α-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome

David B. Shackelford et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Review Biochemistry & Molecular Biology

The GAIT system: a gatekeeper of inflammatory gene expression

Rupak Mukhopadhyay et al.

TRENDS IN BIOCHEMICAL SCIENCES (2009)

Article Biochemistry & Molecular Biology

Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance

Chun-Wun Lu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Immunology

An antiinflammatory role for IKKβ through the inhibition of classical macrophage activation

Carol Ho Yan Fong et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2008)

Review Multidisciplinary Sciences

Integration of metabolism and inflammation by lipid-activated nuclear receptors

Steven J. Bensinger et al.

NATURE (2008)

Review Multidisciplinary Sciences

Cancer-related inflammation

Alberto Mantovani et al.

NATURE (2008)

Review Endocrinology & Metabolism

Innate immunity, insulin resistance and type 2 diabetes

Jose Manuel Fernandez-Real et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2008)

Article Biochemistry & Molecular Biology

GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization

A. Tarze et al.

ONCOGENE (2007)

Article Biochemistry & Molecular Biology

Regulation of HIF-1α stability through S-nitrosylation

Fang Li et al.

MOLECULAR CELL (2007)

Article Medicine, Research & Experimental

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

Carey N. Lumeng et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Cell Biology

Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation

Divya Vats et al.

CELL METABOLISM (2006)

Article Biochemistry & Molecular Biology

The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1α-dependent mechanism

MS Ullah et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Review Biochemistry & Molecular Biology

Multifaceted roles of glycolytic enzymes

JW Kim et al.

TRENDS IN BIOCHEMICAL SCIENCES (2005)

Article Multidisciplinary Sciences

The estrogen-related receptor α (ERRα) functions in PPARγ coactivator 1α (PGC-1α)-induced mitochondrial biogenesis

SN Schreiber et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Immunology

The chemokine system in diverse forms of macrophage activation and polarization

A Mantovani et al.

TRENDS IN IMMUNOLOGY (2004)

Review Biochemistry & Molecular Biology

Hexokinase II: The integration of energy metabolism and control of apoptosis

JG Pastorino et al.

CURRENT MEDICINAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

HIF-1α is essential for myeloid cell-mediated inflammation

T Cramer et al.

Article Medicine, Research & Experimental

Obesity is associated with macrophage accumulation in adipose tissue

SP Weisberg et al.

JOURNAL OF CLINICAL INVESTIGATION (2003)