Journal
FRONTIERS IN PHYSIOLOGY
Volume 9, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fphys.2018.00763
Keywords
atherosclerosis; inflammation; microbiome; cardiovascular disease; physical activity
Categories
Funding
- NIH [5T32HL007824-20, K23HL111339, R03HL135289, R21TR001739, UH2TR002067]
- Leducq Foundation Consortium CAD Genomics
- [R01MH110418]
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Cardiovascular health is a primary research focus, as it is a leading contributor to mortality and morbidity worldwide, and is prohibitively costly for healthcare. Atherosclerosis, the main driver of cardiovascular disease, is now recognized as an inflammatory disorder. Physical activity (PA) may have a more important role in cardiovascular health than previously expected. This review overviews the contribution of PA to cardiovascular health, the inflammatory role of atherosclerosis, and the emerging evidence of the microbiome as a regulator of inflammation.
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