4.6 Review

Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications

Related references

Note: Only part of the references are listed.
Review Immunology

Interleukin-18: Biological properties and role in disease pathogenesis

Gilles Kaplanski

IMMUNOLOGICAL REVIEWS (2018)

Review Biochemistry & Molecular Biology

Mechanisms of NLRP1-Mediated Autoinflammatory Disease in Humans and Mice

Chien-Hsiung Yu et al.

JOURNAL OF MOLECULAR BIOLOGY (2018)

Review Endocrinology & Metabolism

Diabetic cardiomyopathy: a hyperglycaemia- and insulin-resistance-induced heart disease

Guanghong Jia et al.

DIABETOLOGIA (2018)

Review Endocrinology & Metabolism

Medication use for the treatment of diabetes in obese individuals

John P. H. Wilding

DIABETOLOGIA (2018)

Article Medicine, General & Internal

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

P. M. Ridker et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Multidisciplinary Sciences

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner

Stephanie A. Conos et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Biotechnology & Applied Microbiology

Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling

Miaomiao Lu et al.

BIOMED RESEARCH INTERNATIONAL (2017)

Article Medicine, Research & Experimental

Function of NLRP3 in the Pathogenesis and Development of Diabetic Nephropathy

Ying Fu et al.

MEDICAL SCIENCE MONITOR (2017)

Review Physiology

NLRP3 Inflammasome as a Molecular Marker in Diabetic Cardiomyopathy

Beibei Luo et al.

FRONTIERS IN PHYSIOLOGY (2017)

Review Medicine, Research & Experimental

Are targeted therapies for diabetic cardiomyopathy on the horizon?

Mitchel Tate et al.

CLINICAL SCIENCE (2017)

Article Cell Biology

Sulforaphane inhibits multiple inflammasomes through an Nrf2-independent mechanism

Allison J. Greaney et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2016)

Review Endocrinology & Metabolism

Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy

Guanghong Jia et al.

NATURE REVIEWS ENDOCRINOLOGY (2016)

Article Biochemistry & Molecular Biology

Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion

S. A. Conos et al.

CELL DEATH AND DIFFERENTIATION (2016)

Article Cell Biology

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome

Andrew J. Murphy et al.

CELL METABOLISM (2016)

Review Biochemistry & Molecular Biology

The intersection of cell death and inflammasome activation

James E. Vince et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2016)

Article Cardiac & Cardiovascular Systems

Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes

Manasi S. Shah et al.

CIRCULATION RESEARCH (2016)

Article Biochemistry & Molecular Biology

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

Lorenzo Sborgi et al.

EMBO JOURNAL (2016)

Article Cardiac & Cardiovascular Systems

Inflammatory and fibrotic responses of cardiac fibroblasts to myocardial damage associated molecular patterns (DAMPs)

Neil A. Turner

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)

Article Urology & Nephrology

Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy

Khurrum Shahzad et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)

Article Multidisciplinary Sciences

Pore-forming activity and structural autoinhibition of the gasdermin family

Jingjin Ding et al.

NATURE (2016)

Article Multidisciplinary Sciences

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

Xing Liu et al.

NATURE (2016)

Article Multidisciplinary Sciences

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

Robin A. Aglietti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice

Gustavo Monnerat et al.

NATURE COMMUNICATIONS (2016)

Article Multidisciplinary Sciences

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

Eri H. Kobayashi et al.

NATURE COMMUNICATIONS (2016)

Article Cardiac & Cardiovascular Systems

NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis

Geena Paramel Varghese et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2016)

Article Endocrinology & Metabolism

High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells

Hong Feng et al.

JOURNAL OF DIABETES RESEARCH (2016)

Article Pharmacology & Pharmacy

Empagliflozin Protects against Diet-Induced NLRP-3 Inflammasome Activation and Lipid Accumulation

Elisa Benetti et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)

Article Endocrinology & Metabolism

Dipeptidyl peptidase-4 inhibition by Saxagliptin prevents inflammation and renal injury by targeting the Nlrp3/ASC inflammasome

Yochai Birnbaum et al.

BMJ OPEN DIABETES RESEARCH & CARE (2016)

Article Pharmacology & Pharmacy

The Role of NADPH Oxidase in Vascular Disease - Hypertension, Atherosclerosis & Stroke

Stephen P. Gray et al.

CURRENT PHARMACEUTICAL DESIGN (2015)

Article Pharmacology & Pharmacy

Palmitoylethanolamide treatment reduces retinal inflammation in streptozotocin-induced diabetic rats

Irene Paterniti et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2015)

Article Biochemistry & Molecular Biology

Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr-/- mice

Tim Hendrikx et al.

FEBS JOURNAL (2015)

Review Cardiac & Cardiovascular Systems

The Importance of NLRP3 Inflammasome in Heart Failure

Brittany Butts et al.

JOURNAL OF CARDIAC FAILURE (2015)

Article Cardiac & Cardiovascular Systems

Interleukin-18-induced atherosclerosis involves CD36 and NF-κB crosstalk in Apo E-/- mice

Owais Mohammad Bhat et al.

JOURNAL OF CARDIOLOGY (2015)

Article Neurosciences

Expression of the NLRP3 Inflammasome in Carotid Atherosclerosis

Xin Shi et al.

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2015)

Editorial Material Urology & Nephrology

Revisiting inflammation in diabetic nephropathy: the role of the Nlrp3 inflammasome in glomerular resident cells

Norihiko Sakai et al.

KIDNEY INTERNATIONAL (2015)

Article Urology & Nephrology

Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy

Khurrum Shahzad et al.

KIDNEY INTERNATIONAL (2015)

Article Multidisciplinary Sciences

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Nobuhiko Kayagaki et al.

NATURE (2015)

Article Multidisciplinary Sciences

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi et al.

NATURE (2015)

Review Biochemistry & Molecular Biology

Inflammasomes: mechanism of action, role in disease, and therapeutics

Haitao Guo et al.

NATURE MEDICINE (2015)

Article Medicine, General & Internal

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes

Bernard Zinman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Endocrinology & Metabolism

NLRP3 Inflammasome Polymorphism and Macrovascular Complications in Type 2 Diabetes Patients

Jasna Klen et al.

JOURNAL OF DIABETES RESEARCH (2015)

Article Neurosciences

Expression of the NLRP3 Inflammasome in Carotid Atherosclerosis

Xin Shi et al.

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2015)

Review Immunology

Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives

Ema Ozaki et al.

JOURNAL OF INFLAMMATION RESEARCH (2015)

Article Physiology

Hyperuricemia-induced NLRP3 activation of macrophages contributes to the progression of diabetic nephropathy

Su-Mi Kim et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2015)

Article Urology & Nephrology

Sodium/Glucose Cotransporter 2 Inhibitors and Prevention of Diabetic Nephropathy: Targeting the Renal Tubule in Diabetes

Luca De Nicola et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2014)

Review Biochemistry & Molecular Biology

Ambiguities in NLRP3 inflammasome regulation: Is there a role for mitochondria?

Kate E. Lawlor et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)

Article Cardiac & Cardiovascular Systems

Glibenclamide attenuates myocardial injury by lipopolysaccharides in streptozotocin-induced diabetic mice

Jian Cai et al.

CARDIOVASCULAR DIABETOLOGY (2014)

Article Cardiac & Cardiovascular Systems

The interleukin-1 receptor antagonist anakinra improves endothelial dysfunction in streptozotocin-induced diabetic rats

Susana Vallejo et al.

CARDIOVASCULAR DIABETOLOGY (2014)

Editorial Material Cardiac & Cardiovascular Systems

The NLRP3 Inflammasome and Diabetic Cardiomyopathy

Lalit P. Singh

CARDIOVASCULAR DRUGS AND THERAPY (2014)

Article Cardiac & Cardiovascular Systems

Rosuvastatin Alleviates Diabetic Cardiomyopathy by Inhibiting NLRP3 Inflammasome and MAPK Pathways in a Type 2 Diabetes Rat Model

Beibei Luo et al.

CARDIOVASCULAR DRUGS AND THERAPY (2014)

Article Biochemistry & Molecular Biology

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

Alvin Lu et al.

Review Endocrinology & Metabolism

Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes

Nathalie Esser et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2014)

Article Biochemistry & Molecular Biology

Nuclear Factor E2-related Factor-2 (Nrf2) Is Required for NLRP3 and AIM2 Inflammasome Activation

Changcheng Zhao et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Review Cardiac & Cardiovascular Systems

A Novel Pharmacologic Inhibitor of the NLRP3 Inflammasome Limits Myocardial Injury After Ischemia-Reperfusion in the Mouse

Carlo Marchetti et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2014)

Article Immunology

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

Bernardo S. Franklin et al.

NATURE IMMUNOLOGY (2014)

Review Medicine, Research & Experimental

Inflammation and the pathogenesis of diabetic nephropathy

Jun Wada et al.

CLINICAL SCIENCE (2013)

Article Endocrinology & Metabolism

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

Hye-Mi Lee et al.

DIABETES (2013)

Review Cardiac & Cardiovascular Systems

Taking Diabetes to Heart-Deregulation of Myocardial Lipid Metabolism in Diabetic Cardiomyopathy

Marina Bayeva et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)

Review Immunology

Activation and regulation of the inflammasomes

Eicke Latz et al.

NATURE REVIEWS IMMUNOLOGY (2013)

Article Cardiac & Cardiovascular Systems

Caspase-1 Deficiency Decreases Atherosclerosis in Apolipoprotein E-Null Mice

Jessica Gage et al.

CANADIAN JOURNAL OF CARDIOLOGY (2012)

Article Endocrinology & Metabolism

Increased Inflammation in Atherosclerotic Lesions of Diabetic Akita-LDLr-/- Mice Compared to Nondiabetic LDLr-/- Mice

Daniel Engelbertsen et al.

EXPERIMENTAL DIABETES RESEARCH (2012)

Editorial Material Medicine, Research & Experimental

IL-1 and atherosclerosis: a murine twist to an evolving human story

Daniel J. Rader

JOURNAL OF CLINICAL INVESTIGATION (2012)

Review Immunology

The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

P. Menu et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2011)

Article Immunology

Glyburide Is Anti-inflammatory and Associated with Reduced Mortality in Melioidosis

Gavin C. K. W. Koh et al.

CLINICAL INFECTIOUS DISEASES (2011)

Review Biochemistry & Molecular Biology

Understanding the mechanism of IL-1β secretion

Gloria Lopez-Castejon et al.

CYTOKINE & GROWTH FACTOR REVIEWS (2011)

Article Cardiac & Cardiovascular Systems

Anti-apoptotic potential of rosuvastatin pretreatment in murine model of cardiomyopathy

Himanshu Sharma et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2011)

Article Biochemistry & Molecular Biology

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

Bolormaa Vandanmagsar et al.

NATURE MEDICINE (2011)

Article Multidisciplinary Sciences

Inflammasome is a central player in the induction of obesity and insulin resistance

Rinke Stienstra et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse

Eleonora Mezzaroma et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Cardiac & Cardiovascular Systems

Myocardial remodeling after infarction: the role of myofibroblasts

Susanne W. M. van den Borne et al.

NATURE REVIEWS CARDIOLOGY (2010)

Article Cell Biology

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

Mohamed Lamkanfi et al.

JOURNAL OF CELL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

V. Petrilli et al.

CELL DEATH AND DIFFERENTIATION (2007)

Article Hematology

Interleukin-18, the metabolic syndrome, and subclinical atherosclerosis results from the Dallas heart study

Andreas Zirlik et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)

Article Multidisciplinary Sciences

Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency

Eric P. Zorriila et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Inflammation and metabolic disorders

Goekhan S. Hotamisligil

NATURE (2006)

Article Biochemistry & Molecular Biology

Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance

MG Netea et al.

NATURE MEDICINE (2006)

Article Multidisciplinary Sciences

Gout-associated uric acid crystals activate the NALP3 inflammasome

F Martinon et al.

NATURE (2006)

Review Medicine, Research & Experimental

ATP-sensitive potassium channelopathies: focus on insulin secretion

FM Ashcroft

JOURNAL OF CLINICAL INVESTIGATION (2005)

Article Cardiac & Cardiovascular Systems

Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice

R Elhage et al.

CARDIOVASCULAR RESEARCH (2003)

Article Hematology

Lack of interleukin-1β decreases the severity of atherosclerosis in ApoE-deficient mice

H Kirii et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2003)

Review Multidisciplinary Sciences

Biochemistry and molecular cell biology of diabetic complications

M Brownlee

NATURE (2001)