Related references
Note: Only part of the references are listed.Visualizing melanosomes, lipofuscin, and melanolipofuscin in human retinal pigment epithelium using serial block face scanning electron microscopy
Andreas Pollreisz et al.
EXPERIMENTAL EYE RESEARCH (2018)
Mitophagy in neurodegenerative diseases
Carlo Rodolfo et al.
NEUROCHEMISTRY INTERNATIONAL (2018)
Neuraminidases 3 and 4 regulate neuronal function by catabolizing brain gangliosides
Xuefang Pan et al.
FASEB JOURNAL (2017)
Inhibition or Stimulation of Autophagy Affects Early Formation of Lipofuscin-Like Autofluorescence in the Retinal Pigment Epithelium Cell
Lei Lei et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Lipid metabolic perturbation is an early-onset phenotype in adult spinster mutants: a Drosophila model for lysosomal storage disorders
Sarita Hebbar et al.
MOLECULAR BIOLOGY OF THE CELL (2017)
GDE2 is essential for neuronal survival in the postnatal mammalian spinal cord
Clinton Cave et al.
MOLECULAR NEURODEGENERATION (2017)
Conditional loss of progranulin in neurons is not sufficient to cause neuronal ceroid lipofuscinosis-like neuropathology in mice
Terri L. Petkau et al.
NEUROBIOLOGY OF DISEASE (2017)
Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice
Zoe A. Klein et al.
NEURON (2017)
Management Strategies for CLN2 Disease
Ruth E. Williams et al.
PEDIATRIC NEUROLOGY (2017)
Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis
Michael E. Ward et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Altered neurofilament protein expression in the lateral vestibular nucleus in Parkinson's disease
Thomas P. Wellings et al.
EXPERIMENTAL BRAIN RESEARCH (2017)
Mitochondrial contribution to lipofuscin formation
Jeannette Koenig et al.
REDOX BIOLOGY (2017)
Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency
Xiaolai Zhou et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2017)
The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease
Kathleen Atkins et al.
CLINICAL SCIENCE (2016)
Drivers: A Biologically Contextualized, Cross-Inferential View of the Epidemiology of Neurodegenerative Disorders
Jesus de Pedro-Cuesta et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Analysis of lipophilic fluorescent products in blood of Alzheimer's disease patients
Zuzana Chmatalova et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2016)
Diagnosis and misdiagnosis of adult neuronal ceroid lipofuscinosis (Kufs disease)
Samuel F. Berkovic et al.
NEUROLOGY (2016)
Review: Sporadic Parkinson's disease: development and distribution of -synuclein pathology
K. Del Tredici et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2016)
CORE NEUROPATHOLOGICAL ABNORMALITIES IN PROGRANULIN-DEFICIENT MICE ARE PENETRANT ON MULTIPLE GENETIC BACKGROUNDS
T. L. Petkau et al.
NEUROSCIENCE (2016)
Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features
Jesus de Pedro-Cuesta et al.
FRONTIERS IN AGING NEUROSCIENCE (2016)
Manganese-mediated acceleration of age-related hearing loss in mice
Nobutaka Ohgami et al.
SCIENTIFIC REPORTS (2016)
Neuronal ceroid lipofuscinoses
Dragos A. Nita et al.
EPILEPTIC DISORDERS (2016)
Protein Oxidation in Aging: Does It Play a Role in Aging Progression?
Sandra Reeg et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
Experimental therapies in the neuronal ceroid lipofuscinoses
Nicole J. Neverman et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Ethanol-Induced Alterations in Purkinje Neuron Dendrites in Adult and Aging Rats: a Review
Cynthia A. Dlugos
CEREBELLUM (2015)
A novel neuroferritinopathy mouse model (FTL 498InsTC) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits
Federica Maccarinelli et al.
NEUROBIOLOGY OF DISEASE (2015)
An inhibitor of ubiquitin conjugation and aggresome formation
Heeseon An et al.
CHEMICAL SCIENCE (2015)
Degeneration in arousal neurons in chronic sleep disruption modeling sleep apnea
Yan Zhu et al.
FRONTIERS IN NEUROLOGY (2015)
Changes in spectral properties and composition of lipofuscin fluorophores from human-retinal-pigment epithelium with age and pathology
Tatiana B. Feldman et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2015)
Comparative Incidence of Conformational, Neurodegenerative Disorders
Jesus de Pedro-Cuesta et al.
PLOS ONE (2015)
Studying melanin and lipofuscin in RPE cell culture models
Michael E. Boulton
EXPERIMENTAL EYE RESEARCH (2014)
What Goes Wrong with Lon in Ageing?
Kelvin J. A. Davies
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Oral cysteamine bitartrate and N-acetylcysteine for patients with infantile neuronal ceroid lipofuscinosis: a pilot study
Sondra W. Levin et al.
LANCET NEUROLOGY (2014)
Ubiquitination in disease pathogenesis and treatment
Doris Popovic et al.
NATURE MEDICINE (2014)
Huntington disease: natural history, biomarkers and prospects for therapeutics
Christopher A. Ross et al.
NATURE REVIEWS NEUROLOGY (2014)
Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses?
Alexandra Grubman et al.
METALLOMICS (2014)
Inclusion body formation, macroautophagy, and the role of HDAC6 in neurodegeneration
Christiane Richter-Landsberg et al.
ACTA NEUROPATHOLOGICA (2013)
Balance between autophagic pathways preserves retinal homeostasis
Natalia Rodriguez-Muela et al.
AGING CELL (2013)
Dynamics of Lipid Peroxidation-Antioxidant Defense System during Alloxan Diabetes in Rats
I. A. Volchegorskii et al.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2013)
Inhibition of Protein Deubiquitination by PR-619 Activates the Autophagic Pathway in OLN-t40 Oligodendroglial Cells
Veronika Seiberlich et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2013)
Lipofuscin in human glaucomatous optic nerves
J. P. Fernandez de Castro et al.
EXPERIMENTAL EYE RESEARCH (2013)
Classification and Natural History of the Neuronal Ceroid Lipofuscinoses
Jonathan W. Mink et al.
JOURNAL OF CHILD NEUROLOGY (2013)
Alterations in ROS Activity and Lysosomal pH Account for Distinct Patterns of Macroautophagy in LINCL and JNCL Fibroblasts
Jose Manuel Vidal-Donet et al.
PLOS ONE (2013)
Lipofuscin: formation, effects and role of macroautophagy
Annika Hoehn et al.
REDOX BIOLOGY (2013)
Age-Related Changes in the Central Nervous System in Selected Domestic Mammals and Primates
Maciej Firlag et al.
POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ (2013)
Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage
Katherine R. Smith et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2012)
Blood markers of oxidative stress in Alzheimer's disease
Alice Skoumalova et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2012)
Human and rat brain lipofuscin proteome
Philipp Ottis et al.
PROTEOMICS (2012)
Chaperone-mediated autophagy: a unique way to enter the lysosome world
Susmita Kaushik et al.
TRENDS IN CELL BIOLOGY (2012)
Therapeutic Approaches to the Challenge of Neuronal Ceroid Lipofuscinoses
R. Kohan et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2011)
Lipofuscin inhibits the proteasome by binding to surface motifs
Annika Hoehn et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease
Isidre Ferrer et al.
JOURNAL OF NEURAL TRANSMISSION (2011)
Increased iron levels correlate with the selective nigral dopaminergic neuron degeneration in Parkinson's disease
Zhanyun Lv et al.
JOURNAL OF NEURAL TRANSMISSION (2011)
Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years
Heiko Braak et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)
The Hsc/Hsp70 Co-Chaperone Network Controls Antigen Aggregation and Presentation during Maturation of Professional Antigen Presenting Cells
Nadja Kettern et al.
PLOS ONE (2011)
A Deficiency of Ceramide Biosynthesis Causes Cerebellar Purkinje Cell Neurodegeneration and Lipofuscin Accumulation
Lihong Zhao et al.
PLOS GENETICS (2011)
Lipofuscin Hypothesis of Alzheimer's Disease
Giorgio Giaccone et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA (2011)
Ageing and neurodegenerative diseases
Chia-Wei Hung et al.
AGEING RESEARCH REVIEWS (2010)
Mitochondrial Turnover and Aging of Long-Lived Postmitotic Cells: The Mitochondrial-Lysosomal Axis Theory of Aging
Alexei Terman et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
Paula I. Moreira et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Lipofuscin-bound iron is a major intracellular source of oxidants: Role in senescent cells
Annika Hoehn et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Lifelong Calorie Restriction Alleviates Age-Related Oxidative Damage in Peripheral Nerves
Katherine Opalach et al.
REJUVENATION RESEARCH (2010)
Lysosomal Pathology and Osteopetrosis upon Loss of H+-Driven Lysosomal Cl- Accumulation
Stefanie Weinert et al.
SCIENCE (2010)
Deletion of the Huntingtin Polyglutamine Stretch Enhances Neuronal Autophagy and Longevity in Mice
Shuqiu Zheng et al.
PLOS GENETICS (2010)
Molecular architecture of myelinated peripheral nerves is supported by calorie restriction with aging
Sunitha Rangaraju et al.
AGING CELL (2009)
Effects of dietary restriction on mortality and age-related phenotypes in the short-lived fish Nothobranchius furzeri
Eva Terzibasi et al.
AGING CELL (2009)
Cognitive dysfunction and hippocampal changes in experimental type 1 diabetes
Edgardo O. Alvarez et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells
Tuomas Ryhanen et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Heat shock proteins: keys to healthy ageing?
Kenneth J. Rodgers et al.
REDOX REPORT (2009)
The comparative biology of neuromelanin and lipofuscin in the human brain
K. L. Double et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice
Ryo Yamasaki et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2007)
Murine Ccl2/Cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration
Jingsheng Tuo et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
Neurolipofuscin is a measure of age in Panulirus argus, the Caribbean spiny lobster, in Florida
Kerry E. Maxwell et al.
BIOLOGICAL BULLETIN (2007)
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Taichi Hara et al.
NATURE (2006)
Pin1 protein associates with neuronal lipofuscin: Potential consequences in age-related neurodegeneration
Lida Hashemzadeh-Bonehi et al.
EXPERIMENTAL NEUROLOGY (2006)
Biomarkers of oxidative damage in human disease
I Dalle-Donne et al.
CLINICAL CHEMISTRY (2006)
Murine cathepsin F deficiency causes neuronal lipofuscinosis and late-onset neurological disease
CH Tang et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Age-associated changes in protein oxidation and proteasome activities in rat brain: Modulation by antioxidants
MMA El Mohsen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Aggregates of oxidized proteins (lipofuscin) induce apoptosis through proteasome inhibition and dysregulation of proapoptotic proteins
SR Powell et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration
D Kasper et al.
EMBO JOURNAL (2005)
Impaired proteasome activity and accumulation of ubiquitinated substrates in a hereditary neuropathy model
J Fortun et al.
JOURNAL OF NEUROCHEMISTRY (2005)
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
N Mizushima et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Experimental diabetes accelerates accumulation of fluorescent pigments in rat trigeminal neurons
A Sugaya et al.
BRAIN RESEARCH (2004)
Lipofuscin
A Terman et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Perineuronal nets potentially protect against oxidative stress
M Morawski et al.
EXPERIMENTAL NEUROLOGY (2004)
Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain
JN Keller et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease
T Grune et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)
Neurological aspects of osteopetrosis
CG Steward
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2003)
Staging of brain pathology related to sporadic Parkinson's disease
H Braak et al.
NEUROBIOLOGY OF AGING (2003)
Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease
GE Meredith et al.
BRAIN RESEARCH (2002)
Dementia and Alzheimer disease incidence - A prospective cohort study
WA Kukull et al.
ARCHIVES OF NEUROLOGY (2002)
Lipofuscin: Mechanisms of age-related accumulation and influence on cell function
UT Brunk et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis
M Yoshikawa et al.
GENES TO CELLS (2002)
Sequential histochemical studies of neuronal lipofuscin in human cerebral cortex from the first to the ninth decade of life
SH Benavides et al.
ARCHIVES OF GERONTOLOGY AND GERIATRICS (2002)
Age-related changes in protein oxidation and proteolysis in mammalian cells
T Grune et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2001)
Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster
Y Nakano et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Garbage catastrophe theory of aging: imperfect removal of oxidative damage?
A Terman
REDOX REPORT (2001)
Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons
M Koike et al.
JOURNAL OF NEUROSCIENCE (2000)