Journal
CURRENT UROLOGY REPORTS
Volume 19, Issue 1, Pages -Publisher
SPRINGER
DOI: 10.1007/s11934-018-0763-6
Keywords
Pediatric urology; Genitourinary microbiome; Urologic diseases; Urinary incontinence; Urolithiasis
Categories
Funding
- NICHD NIH HHS [K12 HD001399] Funding Source: Medline
- NIDDK NIH HHS [R01 DK113504] Funding Source: Medline
Ask authors/readers for more resources
Purpose of Review In this review, we highlight the effects of the microbiome on urologic diseases that affect the pediatric patient. Recent Findings Perturbations in the urinary microbiome have been shown to be associated with a number of urologic diseases affecting children, namely urinary tract infection, overactive bladder/urge urinary incontinence, and urolithiasis. Summary Recently, improved cultivation and sequencing technologies have allowed for the discovery of a significant and diverse microbiome in the bladder, previously assumed to be sterile. Early studies aimed to identify the resident bacterial species and demonstrate the efficacy of sequencing and enhanced quantitative urine culture. More recently, research has sought to elucidate the association between the microbiome and urologic disease, as well as to demonstrate effects of manipulation of the microbiome on various urologic pathologies. With an improved appreciation for the impact of the urinary microbiome on urologic disease, researchers have begun to explore the impact of these resident bacteria in pediatric urology.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available