Related references
Note: Only part of the references are listed.Protein tyrosine phosphatase PTPN22 has dual roles in promoting pathogen versus homeostatic-driven CD8 T-cell responses
Tatiana Jofra et al.
IMMUNOLOGY AND CELL BIOLOGY (2017)
Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations
Akihiro Hoshino et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2017)
Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity
Yumi Nakayama et al.
JOURNAL OF IMMUNOLOGY (2017)
Lyn and Fyn function as molecular switches that control immunoreceptors to direct homeostasis or inflammation
Sanae Ben Mkaddem et al.
NATURE COMMUNICATIONS (2017)
Genetic advances in systemic lupus erythematosus: an update
Lingyan Chen et al.
CURRENT OPINION IN RHEUMATOLOGY (2017)
BACH transcription factors in innate and adaptive immunity
Kazuhiko Igarashi et al.
NATURE REVIEWS IMMUNOLOGY (2017)
Targeting CD22 with the monoclonal antibody epratuzumab modulates human B-cell maturation and cytokine production in response to Toll-like receptor 7 (TLR7) and B-cell receptor (BCR) signaling
Natalia V. Giltiay et al.
ARTHRITIS RESEARCH & THERAPY (2017)
Memory B cells: total recall
Tri Giang Phan et al.
CURRENT OPINION IN IMMUNOLOGY (2017)
Kruppel-like factor4 regulates PRDM1 expression through binding to an autoimmune risk allele
Su Hwa Jang et al.
JCI INSIGHT (2017)
The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans
Elizabeth M. Dam et al.
CLINICAL IMMUNOLOGY (2016)
The SLE variant Ala71Thr of BLK severely decreases protein abundance and binding to BANK1 through impairment of the SH3 domain function
A. Diaz-Barreiro et al.
GENES AND IMMUNITY (2016)
The genetic basis of systemic lupus erythematosus: What are the risk factors and what have we learned
Maria Teruel et al.
JOURNAL OF AUTOIMMUNITY (2016)
B-cell subsets, signaling and their roles in secretion of autoantibodies
S. Iwata et al.
LUPUS (2016)
Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus
David L. Morris et al.
NATURE GENETICS (2016)
Systemic lupus erythematosus
Arvind Kaul et al.
NATURE REVIEWS DISEASE PRIMERS (2016)
Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression
Xiaoming Lu et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2015)
UBE2L3 Polymorphism Amplifies NF-κB Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases
Myles J. Lewis et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2015)
Requirement for Transcription Factor Ets1 in B Cell Tolerance to Self-Antigens
Lisa Russell et al.
JOURNAL OF IMMUNOLOGY (2015)
Autoimmune Disease-Associated Haplotypes of BLK Exhibit Lowered Thresholds for B Cell Activation and Expansion of Ig Class-Switched B Cells
Kim R. Simpfendorfer et al.
ARTHRITIS & RHEUMATOLOGY (2015)
Defects in germinal center selection in SLE
Megan Woods et al.
FRONTIERS IN IMMUNOLOGY (2015)
Genetic and epigenetic fine mapping of causal autoimmune disease variants
Kyle Kai-How Farh et al.
NATURE (2015)
T/B-cell interactions are more transient in response to weak stimuli in SLE-prone mice
Parisa Sinai et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2014)
MHC associations with clinical and autoantibody manifestations in European SLE
D. L. Morris et al.
GENES AND IMMUNITY (2014)
Neutrophil-Mediated IFN Activation in the Bone Marrow Alters B Cell Development in Human and Murine Systemic Lupus Erythematosus
Arumugam Palanichamy et al.
JOURNAL OF IMMUNOLOGY (2014)
Single nucleotide polymorphisms in genes encoding toll-like receptors 7, 8 and 9 in Danish patients with systemic lupus erythematosus
C. Enevold et al.
MOLECULAR BIOLOGY REPORTS (2014)
Bone marrow analysis of immune cells and apoptosis in patients with systemic lupus erythematosus
J. W. Park et al.
LUPUS (2014)
Stage-specific control of early B cell development by the transcription factor Ikaros
Tanja A. Schwickert et al.
NATURE IMMUNOLOGY (2014)
Autoantibodies from long-lived 'memory' plasma cells of NZB/W mice drive immune complex nephritis
Qingyu Cheng et al.
ANNALS OF THE RHEUMATIC DISEASES (2013)
Aberrant B Cell Selection and Activation in Systemic Lupus Erythematosus
Laurens P. Kil et al.
INTERNATIONAL REVIEWS OF IMMUNOLOGY (2013)
Chromatin marks identify critical cell types for fine mapping complex trait variants
Gosia Trynka et al.
NATURE GENETICS (2013)
The Genotype-Tissue Expression (GTEx) project
John Lonsdale et al.
NATURE GENETICS (2013)
Systematic identification of trans eQTLs as putative drivers of known disease associations
Harm-Jan Westra et al.
NATURE GENETICS (2013)
The dual effect of the lupus-associated polymorphism rs10516487 on BANK1 gene expression and protein localization
S. V. Kozyrev et al.
GENES AND IMMUNITY (2012)
CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation
Nataly Manjarrez-Orduno et al.
NATURE GENETICS (2012)
The establishment of early B cell tolerance in humans: lessons from primary immunodeficiency diseases
Eric Meffre
YEAR IN HUMAN AND MEDICAL GENETICS: INBORN ERRORS OF IMMUNITY II (2011)
Plasma cells in systemic lupus erythematosus: The long and short of it all
Zheng Liu et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans
Laurence Menard et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
The role of defective clearance of apoptotic cells in systemic autoimmunity
Luis E. Munoz et al.
NATURE REVIEWS RHEUMATOLOGY (2010)
Genetic associations of LYN with systemic lupus erythematosus
R. Lu et al.
GENES AND IMMUNITY (2009)
Cutting Edge: The PTPN22 Allelic Variant Associated with Autoimmunity Impairs B Cell Signaling
Adrian F. Arechiga et al.
JOURNAL OF IMMUNOLOGY (2009)
Association of the co-stimulator OX40L with systemic lupus erythematosus
Harinder Manku et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2009)
Mechanisms and functions for the duration of intercellular contacts made by lymphocytes
Daniel M. Davis
NATURE REVIEWS IMMUNOLOGY (2009)
Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus -: Delineation by expression of CD27, IgD, and CD95
Annett M. Jacobi et al.
ARTHRITIS AND RHEUMATISM (2008)
Cytokine-producing B lymphocytes - key regulators of immunity
Frances E. Lund
CURRENT OPINION IN IMMUNOLOGY (2008)
IRAK-4-and MyD88-Dependent Pathways Are Essential for the Removal of Developing Autoreactive B Cells in Humans
Isabelle Isnardi et al.
IMMUNITY (2008)
Pathogenic Autoantibodies in Systemic Lupus Erythematosus Are Derived from Both Self-Reactive and Non-Self-Reactive B Cells
Jie Zhang et al.
MOLECULAR MEDICINE (2008)
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
John B. Harley et al.
NATURE GENETICS (2008)
Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros
Damien Reynaud et al.
NATURE IMMUNOLOGY (2008)
The genetics of SLE: an update in the light of genome-wide association studies
B. Rhodes et al.
RHEUMATOLOGY (2008)
Interferon regulatory factors 4 and 8 induce the expression of Ikaros and Aiolos to down-regulate pre-B-cell receptor and promote cell-cycle withdrawal in pre-B-cell development
Shibin Ma et al.
BLOOD (2008)
Interleukin-6 is responsible for aberrant B-cell receptor-mediated regulation of RAG expression in systemic lupus erythematosus
Sophie Hillion et al.
IMMUNOLOGY (2007)
CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance
Maxime Herve et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Pre-BCR signals and the control of Ig gene rearrangements
JK Geier et al.
SEMINARS IN IMMUNOLOGY (2006)
Lyn dericiency in B cells from patients with systemic lupus erythematosus: comment on the article by Flores-Borja et al
SNC Liossis et al.
ARTHRITIS AND RHEUMATISM (2006)
Decreased Lyn expression and translocation to lipid raft signaling domains in B lymphocytes from patients with systemic lupus erythematosus
F Flores-Borja et al.
ARTHRITIS AND RHEUMATISM (2005)
Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF
R Lesley et al.
IMMUNITY (2004)
Aiolos is required for the generation of high affinity bone marrow plasma cells responsible for long-term immunity
M Cortés et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
Flow cytometric assessment of the signaling status of human B lymphocytes from normal and autoimmune individuals
AC Grammer et al.
ARTHRITIS RESEARCH & THERAPY (2004)
Development of autoantibodies before the clinical onset of systemic lupus erythematosus
MR Arbuckle et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
B cell abnormalities in systemic lupus erythematosus
AC Grammer et al.
ARTHRITIS RESEARCH & THERAPY (2003)
Expression of recombination activating genes 1 and 2 in peripheral B cells of patients with systemic lupus erythematosus
HJ Girschick et al.
ARTHRITIS AND RHEUMATISM (2002)