4.7 Review

Gut microbial communities modulating brain development and function

Journal

GUT MICROBES
Volume 3, Issue 4, Pages 366-373

Publisher

TAYLOR & FRANCIS INC
DOI: 10.4161/gmic.21287

Keywords

brain development; gut microbiota; behavior; probiotics; microbiota-gut-brain axis

Funding

  1. Qatar University
  2. VR
  3. Singapore Millenium Foundation
  4. Cancerfonden
  5. EU-project TORNADO

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Mammalian brain development is initiated in utero and internal and external environmental signals can affect this process all the way until adulthood. Recent observations suggest that one such external cue is the indigenous microbiota which has been shown to affect developmental programming of the brain. This may have consequences for brain maturation and function that impact on cognitive functions later in life. This review discusses these recent findings from a developmental perspective.

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