Journal
MICROMACHINES
Volume 9, Issue 7, Pages -Publisher
MDPI
DOI: 10.3390/mi9070327
Keywords
3D printing; sacrificial materials; microfluidics; removing efficiency; quantification
Categories
Funding
- National Key Research and Development Program of China [2016YFC0102000, 2017YFA0205202]
- National Natural Science Foundation of China [81772011]
- Social Development of Key Science and Technology Program of Shaanxi Province [2016SF-235]
- Fundamental Research Funds for the Central Universities [JB161208, JB171208, XJS15054]
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Three-dimensional (3D) printing will create a revolution in the field of microfluidics due to fabricating truly three-dimensional channels in a single step. During the 3D-printing process, sacrificial materials are usually needed to fulfill channels inside and support the printed chip outside. Removing sacrificial materials after printing is obviously crucial for applying these 3D printed chips to microfluidics. However, there are few standard methods to address this issue. In this paper, engineering techniques of removing outer and inner sacrificial materials were studied. Meanwhile, quantification methods of removal efficiency for outer and inner sacrificial materials were proposed, respectively. For outer sacrificial materials, a hot bath in vegetable oil can remove 89.9% +/- 0.1% of sacrificial materials, which is better than mechanics removal, hot oven heating, and an ethanol bath. For inner sacrificial materials, injecting 70 degrees C vegetable oil for 720 min is an optimized approach because of the uniformly high transmittance (93.8% +/- 6.8%) and no obvious deformation. For the industrialization of microfluidics, the cost-effective removing time is around 10 min, which considers the balance between time cost and chip transmittance. The optimized approach and quantification methods presented in this paper show general engineering sacrificial materials removal techniques, which promote removing sacrificial materials from 3D-printed microfluidics chips and take 3D printing a step further in microfluidic applications.
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