Journal
THERAPEUTIC DELIVERY
Volume 3, Issue 2, Pages 181-194Publisher
FUTURE SCI LTD
DOI: 10.4155/TDE.11.156
Keywords
Reticulo-endothelial system; Phagocytosis; Thromboprophylaxis; Enhanced permeability and retention effect; Margination; Stimuli-responsive nanoplatform
Categories
Funding
- National Science Foundation [CBET-1113040, CBET-1067502, DMR-0923299]
- NIH [EB009786]
- Div Of Chem, Bioeng, Env, & Transp Sys
- Directorate For Engineering [1113040] Funding Source: National Science Foundation
Ask authors/readers for more resources
The design of nanoparticle (NP) size, shape and surface chemistry has a significant impact on their performance. While the influences of the particle size and surface chemistry on drug delivery have been studied extensively, little is known about the effect of particle shapes on nanomedicine. In this perspective article, we discuss recent progress on the design and fabrication of NPs of various shapes and their unique delivery properties. The shapes of these drug carriers play an important role in therapeutic delivery processes, such as particle adhesion, distribution and cell internalization. We envision that stimuli-responsive NPs, which actively change their shapes and other properties, might pave way to the next generation of nanomedicine.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available