Journal
EMERGING INFECTIOUS DISEASES
Volume 18, Issue 1, Pages 86-90Publisher
CENTERS DISEASE CONTROL
DOI: 10.3201/eid1801.110556
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- Merck
- Merck and Schering
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We report 20 episodes of infection caused by acquired echinocandin-resistant Candida spp. harboring diverse and new Fksp mutations. For 12 patients, initial isolates (low MIC, wild-type Fksp sequence) and subsequent isolates (after caspofungin treatment, high MIC, mutated Fksp) were genetically related.
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