4.6 Review

Multifunctional bacterial imaging and therapy systems

Journal

JOURNAL OF MATERIALS CHEMISTRY B
Volume 6, Issue 32, Pages 5198-5214

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8tb01519h

Keywords

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Funding

  1. National Natural Science Foundation of China [21374079, 21674080, 51473061]
  2. 131 talents program of Tianjin
  3. Key program of Tianjin Municipal Natural Science Foundation [18JCZDJC37700]
  4. Training Project of Innovation Team of Colleges and Universities in Tianjin [TD13-5020]
  5. Jilin Province-University Cooperative Construction Project-Special Funds for New Materials [SXGJSF2017-3]
  6. Leading Talents Program of the Tianjin Educational Committee

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Bacterial infections have severely affected human health, leading to a considerable number of human deaths. Inevitably direct and indirect contacts with medical devices, food packing and daily supplies with harmful bacteria are among the major transmission routes of bacterial infections. Effective bacterial theranostic systems that combine diagnostic functions and therapeutic effects have received extensive attention due to their excellent features including high efficiency, real-time performance and low drug resistance. In this review article, we summarize the recent advances of antibacterial materials including natural antibacterial compounds, quaternary ammonium polymers, and inorganic or hybrid nanoparticles with the dual functions of detection and imaging. In particular, multiple imaging modalities and antibacterial modalities are systematically discussed in order to provide a better understanding of modern theranostics.

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