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Subcellular Specialization and Organelle Behavior in Germ Cells

Journal

GENETICS
Volume 208, Issue 1, Pages 19-51

Publisher

GENETICS SOCIETY AMERICA
DOI: 10.1534/genetics.117.300184

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Funding

  1. Howard Hughes Medical Institute
  2. National Institute of General Medical Sciences [R01 GM-118308]
  3. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM118308] Funding Source: NIH RePORTER

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Gametes, eggs and sperm, are the highly specialized cell types on which the development of new life solely depends. Although all cells share essential organelles, such as the ER (endoplasmic reticulum), Golgi, mitochondria, and centrosomes, germ cells display unique regulation and behavior of organelles during gametogenesis. These germ cell-specific functions of organelles serve critical roles in successful gamete production. In this chapter, I will review the behaviors and roles of organelles during germ cell differentiation.

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