4.6 Review

Protein Engineering for Nicotinamide Coenzyme Specificity in Oxidoreductases: Attempts and Challenge

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

A General Tool for Engineering the NAD/NADP Cofactor Preference of Oxidoreductases

Jackson K. B. Cahn et al.

ACS SYNTHETIC BIOLOGY (2017)

Article Biochemistry & Molecular Biology

Isolation and characterization of a thermostable F420:NADPH oxidoreductase from Thermobifida fusca

Hemant Kumar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2017)

Article Biochemistry & Molecular Biology

Engineering of alanine dehydrogenase from Bacillus subtilis for novel cofactor specificity

Alexandra Lerchner et al.

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY (2016)

Article Biotechnology & Applied Microbiology

Alternative Biotransformation of Retinal to Retinoic Acid or Retinol by an Aldehyde Dehydrogenase from Bacillus cereus

Seung-Hye Hong et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2016)

Article Biochemistry & Molecular Biology

Switch in Cofactor Specificity of a Baeyer-Villiger Monooxygenase

Andy Beier et al.

CHEMBIOCHEM (2016)

Article Biotechnology & Applied Microbiology

A NADH-accepting imine reductase variant: Immobilization and cofactor regeneration by oxidative deamination

Martin Gand et al.

JOURNAL OF BIOTECHNOLOGY (2016)

Article Chemistry, Multidisciplinary

Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes

Tanja Knaus et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Article Biochemistry & Molecular Biology

A computational strategy for altering an enzyme in its cofactor preference to NAD(H) and/or NADP(H)

Dongbing Cui et al.

FEBS JOURNAL (2015)

Article Biochemistry & Molecular Biology

Substitutions at the cofactor phosphate-binding site of a clostridial alcohol dehydrogenase lead to unexpected changes in substrate specificity

Danielle J. Maddock et al.

PROTEIN ENGINEERING DESIGN & SELECTION (2015)

Article Biochemistry & Molecular Biology

Aldehyde dehydrogenase enzyme ALDH3H1 from Arabidopsis thaliana: Identification of amino acid residues critical for cofactor specificity

Naim Stiti et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2014)

Article Biochemistry & Molecular Biology

Alteration of coenzyme specificity of malate dehydrogenase from Streptomyces coelicolor A3(2) by site-directed mutagenesis

Y. D. Ge et al.

GENETICS AND MOLECULAR RESEARCH (2014)

Article Biotechnology & Applied Microbiology

Improving the NADH-cofactor specificity of the highly active AdhZ3 and AdhZ2 from Escherichia coli K-12

Andre Pick et al.

JOURNAL OF BIOTECHNOLOGY (2014)

Article Biotechnology & Applied Microbiology

Uncovering rare NADH-preferring ketol-acid reductoisomerases

S. Brinkmann-Chen et al.

METABOLIC ENGINEERING (2014)

Review Chemistry, Physical

Is Simpler Better? Synthetic Nicotinamide Cofactor Analogues for Redox Chemistry

Caroline E. Paul et al.

ACS CATALYSIS (2014)

Article Biochemistry & Molecular Biology

COFACTOR SPECIFICITY ENGINEERING OF STREPTOCOCCUS MUTANS NADH OXIDASE 2 FOR NAD( P)+ REGENERATION IN BIOCATALYTIC OXIDATIONS

Barbara Petschacher et al.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2014)

Article Biotechnology & Applied Microbiology

Engineering of formate dehydrogenase: synergistic effect of mutations affecting cofactor specificity and chemical stability

Kathrin Hoelsch et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2013)

Article Multidisciplinary Sciences

General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH

Sabine Brinkmann-Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

Reversal of the extreme coenzyme selectivity of Clostridium symbiosum glutamate dehydrogenase

Michael A. Sharkey et al.

FEBS JOURNAL (2012)

Article Biotechnology & Applied Microbiology

Improved Product-Per-Glucose Yields in P450-Dependent Propane Biotransformations Using Engineered Escherichia coli

Rudi Fasan et al.

BIOTECHNOLOGY AND BIOENGINEERING (2011)

Article Biotechnology & Applied Microbiology

Cloning, characterization, and engineering of fungal L-arabinitol dehydrogenases

Byoungjin Kim et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)

Article Biotechnology & Applied Microbiology

Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca

Hanna M. Dudek et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)

Article Biotechnology & Applied Microbiology

A novel NADP+-dependent formate dehydrogenase from Burkholderia stabilis 15516: Screening, purification and characterization

Rujirat Hatrongjit et al.

ENZYME AND MICROBIAL TECHNOLOGY (2010)

Article Biotechnology & Applied Microbiology

Monooxygenases as biocatalysts: Classification, mechanistic aspects and biotechnological applications

D. E. Torres Pazmino et al.

JOURNAL OF BIOTECHNOLOGY (2010)

Article Biotechnology & Applied Microbiology

Relaxing the coenzyme specificity of 1,3-propanediol oxidoreductase from Klebsiella pneumoniae by rational design

Chengwei Ma et al.

JOURNAL OF BIOTECHNOLOGY (2010)

Article Biochemistry & Molecular Biology

Structure and Engineering of L-Arabinitol 4-Dehydrogenase from Neurospora crassa

Brian Bae et al.

JOURNAL OF MOLECULAR BIOLOGY (2010)

Article Biotechnology & Applied Microbiology

Ser67Asp and His68Asp Substitutions in Candida parapsilosis Carbonyl Reductase Alter the Coenzyme Specificity and Enantioselectivity of Ketone Reduction

Rongzhen Zhang et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)

Article Biochemistry & Molecular Biology

Induced Fit and Equilibrium Dynamics for High Catalytic Efficiency in Ferredoxin-NADP(H) Reductases

Dario H. Paladini et al.

BIOCHEMISTRY (2009)

Article Biotechnology & Applied Microbiology

Reversal of Coenzyme Specificity of 2,3-Butanediol Dehydrogenase From Saccharomyces cerevisae and In Vivo Functional Analysis

Maryam Ehsani et al.

BIOTECHNOLOGY AND BIOENGINEERING (2009)

Article Biochemistry & Molecular Biology

Alteration of coenzyme specificity in halophilic NAD(P)+ glucose dehydrogenase by site-directed mutagenesis

C. Pire et al.

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2009)

Article Biochemistry & Molecular Biology

Site-saturation mutagenesis of formate dehydrogenase from Candida bodinii creating effective NADP(+)-dependent FDH enzymes

Weihua Wu et al.

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2009)

Article Biochemistry & Molecular Biology

Computational design of Candida boidinii xylose reductase for altered cofactor specificity

George A. Khoury et al.

PROTEIN SCIENCE (2009)

Article Biotechnology & Applied Microbiology

Altering coenzyme specificity of Pichia stipitis xylose reductase by the semi-rational approach CASTing

Ling Liang et al.

MICROBIAL CELL FACTORIES (2007)

Article Biotechnology & Applied Microbiology

Rational design of novel mutants of fungal 17β-hydroxy steroid dehydrogenase

Katja Kristan et al.

JOURNAL OF BIOTECHNOLOGY (2007)

Article Multidisciplinary Sciences

Direct demonstration of an adaptive constraint

Stephen P. Miller et al.

SCIENCE (2006)

Article Biochemistry & Molecular Biology

Structure-guided engineering of xylitol dehydrogenase cosubstrate specificity

AH Ehrensberger et al.

STRUCTURE (2006)

Article Biochemistry & Molecular Biology

Complete reversal of coenzyme specificity of isocitrate dehydrogenase from Haloferax volcanii

A Rodríguez-Arnedo et al.

PROTEIN JOURNAL (2005)

Article Chemistry, Applied

Catalytic hydroxylation in biphasic systems using CYP102A1 mutants

SC Maurer et al.

ADVANCED SYNTHESIS & CATALYSIS (2005)

Article Biochemistry & Molecular Biology

Conversion of cofactor specificities of alanine dehydrogenases by site-directed mutagenesis

H Ashida et al.

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2004)

Article Biochemistry & Molecular Biology

Identifying determinants of NADPH specificity in Baeyer-Villiger monooxygenases

NM Kamerbeek et al.

EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Complete reversal of coenzyme specificity by concerted mutation of three consecutive residues in alcohol dehydrogenase

A Rosell et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Relaxing the nicotinamide cofactor specificity of phosphite dehydrogenase by rational design

R Woodyer et al.

BIOCHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Engineering and characterization of a NADPH-utilizing cytochrome b5 reductase

CC Marohnic et al.

BIOCHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Modification of the nucleotide cofactor-binding site of cytochrome P-450 reductase to enhance turnover with NADH in vivo

CL Elmore et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Engineering of coenzyme specificity of formate dehydrogenase from Saccharomyces cerevisiae

AE Serov et al.

BIOCHEMICAL JOURNAL (2002)

Article Biochemistry & Molecular Biology

Probing the determinants of coenzyme specificity in ferredoxin-NADP+ reductase by site-directed mutagenesis

M Medina et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biotechnology & Applied Microbiology

A single mutation in the NAD-specific formate dehydrogenase from Candida methylica allows the enzyme to use NADP

N Gul-Karaguler et al.

BIOTECHNOLOGY LETTERS (2001)

Article Multidisciplinary Sciences

Engineering of a functional human NADH-dependent cytochrome P450 system

O Döhr et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

Inhibition of the thioredoxin-dependent activation of the NADP-malate dehydrogenase and cofactor specificity

I Schepens et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)