Related references
Note: Only part of the references are listed.A General Tool for Engineering the NAD/NADP Cofactor Preference of Oxidoreductases
Jackson K. B. Cahn et al.
ACS SYNTHETIC BIOLOGY (2017)
Isolation and characterization of a thermostable F420:NADPH oxidoreductase from Thermobifida fusca
Hemant Kumar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Engineering the cofactor specificity of an alcohol dehydrogenase via single mutations or insertions distal to the 2′-phosphate group of NADP(H)
Kusum Solanki et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2017)
Engineering of alanine dehydrogenase from Bacillus subtilis for novel cofactor specificity
Alexandra Lerchner et al.
BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY (2016)
Alternative Biotransformation of Retinal to Retinoic Acid or Retinol by an Aldehyde Dehydrogenase from Bacillus cereus
Seung-Hye Hong et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2016)
Extreme makeover: Engineering the activity of a thermostable alcohol dehydrogenase (AdhD) from Pyrococcus furiosus
Kusum Solanki et al.
BIOTECHNOLOGY JOURNAL (2016)
Switch in Cofactor Specificity of a Baeyer-Villiger Monooxygenase
Andy Beier et al.
CHEMBIOCHEM (2016)
A NADH-accepting imine reductase variant: Immobilization and cofactor regeneration by oxidative deamination
Martin Gand et al.
JOURNAL OF BIOTECHNOLOGY (2016)
Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes
Tanja Knaus et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)
Extreme makeover: Engineering the activity of a thermostable alcohol dehydrogenase (AdhD) from Pyrococcus furiosus
Kusum Solanki et al.
BIOTECHNOLOGY JOURNAL (2016)
A computational strategy for altering an enzyme in its cofactor preference to NAD(H) and/or NADP(H)
Dongbing Cui et al.
FEBS JOURNAL (2015)
Substitutions at the cofactor phosphate-binding site of a clostridial alcohol dehydrogenase lead to unexpected changes in substrate specificity
Danielle J. Maddock et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2015)
Aldehyde dehydrogenase enzyme ALDH3H1 from Arabidopsis thaliana: Identification of amino acid residues critical for cofactor specificity
Naim Stiti et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2014)
Alteration of coenzyme specificity of malate dehydrogenase from Streptomyces coelicolor A3(2) by site-directed mutagenesis
Y. D. Ge et al.
GENETICS AND MOLECULAR RESEARCH (2014)
Structure-based Conversion of the Coenzyme Requirement of a Short-chain Dehydrogenase/Reductase Involved in Bacterial Alginate Metabolism
Ryuichi Takase et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Improving the NADH-cofactor specificity of the highly active AdhZ3 and AdhZ2 from Escherichia coli K-12
Andre Pick et al.
JOURNAL OF BIOTECHNOLOGY (2014)
Exploring nicotinamide cofactor promiscuity in NAD(P)H-dependent flavin containing monooxygenases (FMOs) using natural variation within the phosphate binding loop. Structure and activity of FMOs from Cellvibrio sp. BR and Pseudomonas stutzeri NF13
Chantel N. Jensen et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2014)
Uncovering rare NADH-preferring ketol-acid reductoisomerases
S. Brinkmann-Chen et al.
METABOLIC ENGINEERING (2014)
A de novo NADPH generation pathway for improving lysine production of Corynebacterium glutamicum by rational design of the coenzyme specificity of glyceraldehyde 3-phosphate dehydrogenase
Rajesh Reddy Bommareddy et al.
METABOLIC ENGINEERING (2014)
Is Simpler Better? Synthetic Nicotinamide Cofactor Analogues for Redox Chemistry
Caroline E. Paul et al.
ACS CATALYSIS (2014)
COFACTOR SPECIFICITY ENGINEERING OF STREPTOCOCCUS MUTANS NADH OXIDASE 2 FOR NAD( P)+ REGENERATION IN BIOCATALYTIC OXIDATIONS
Barbara Petschacher et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2014)
Engineering of formate dehydrogenase: synergistic effect of mutations affecting cofactor specificity and chemical stability
Kathrin Hoelsch et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2013)
Converting NAD-Specific Inositol Dehydrogenase to an Efficient NADP-Selective Catalyst, with a Surprising Twist
Hongyan Zheng et al.
BIOCHEMISTRY (2013)
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
Sabine Brinkmann-Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Mutations of an NAD(P)H-dependent flavoprotein monooxygenase that influence cofactor promiscuity and enantioselectivity
Chantel N. Jensen et al.
FEBS OPEN BIO (2013)
A Single Tyrosine Hydroxyl Group Almost Entirely Controls the NADPH Specificity of Plasmodium falciparum Ferredoxin-NADP+ Reductase
Sara Baroni et al.
BIOCHEMISTRY (2012)
Reversal of the extreme coenzyme selectivity of Clostridium symbiosum glutamate dehydrogenase
Michael A. Sharkey et al.
FEBS JOURNAL (2012)
Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: Implications for the mechanism of electron transfer in the P450 BM3 dimer
Hazel M. Girvan et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)
Improved Product-Per-Glucose Yields in P450-Dependent Propane Biotransformations Using Engineered Escherichia coli
Rudi Fasan et al.
BIOTECHNOLOGY AND BIOENGINEERING (2011)
Re-engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild-type enzyme
Marina Capone et al.
FEBS JOURNAL (2011)
Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli
Sabine Bastian et al.
METABOLIC ENGINEERING (2011)
Cloning, characterization, and engineering of fungal L-arabinitol dehydrogenases
Byoungjin Kim et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)
Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca
Hanna M. Dudek et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)
A novel NADP+-dependent formate dehydrogenase from Burkholderia stabilis 15516: Screening, purification and characterization
Rujirat Hatrongjit et al.
ENZYME AND MICROBIAL TECHNOLOGY (2010)
Engineering Cofactor Preference of Ketone Reducing Biocatalysts: A Mutagenesis Study on a γ-Diketone Reductase from the Yeast Saccharomyces cerevisiae Serving as an Example
Michael Katzberg et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2010)
Monooxygenases as biocatalysts: Classification, mechanistic aspects and biotechnological applications
D. E. Torres Pazmino et al.
JOURNAL OF BIOTECHNOLOGY (2010)
Relaxing the coenzyme specificity of 1,3-propanediol oxidoreductase from Klebsiella pneumoniae by rational design
Chengwei Ma et al.
JOURNAL OF BIOTECHNOLOGY (2010)
Structure and Engineering of L-Arabinitol 4-Dehydrogenase from Neurospora crassa
Brian Bae et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Ser67Asp and His68Asp Substitutions in Candida parapsilosis Carbonyl Reductase Alter the Coenzyme Specificity and Enantioselectivity of Ketone Reduction
Rongzhen Zhang et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2009)
Induced Fit and Equilibrium Dynamics for High Catalytic Efficiency in Ferredoxin-NADP(H) Reductases
Dario H. Paladini et al.
BIOCHEMISTRY (2009)
Reversal of Coenzyme Specificity of 2,3-Butanediol Dehydrogenase From Saccharomyces cerevisae and In Vivo Functional Analysis
Maryam Ehsani et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
Reversal of coenzyme specificity and improvement of catalytic efficiency of Pichia stipitis xylose reductase by rational site-directed mutagenesis
Qi-Kai Zeng et al.
BIOTECHNOLOGY LETTERS (2009)
Xylose reductase from the thermophilic fungus Talaromyces emersonii: cloning and heterologous expression of the native gene (Texr) and a double mutant (Texr K271R+N273D) with altered coenzyme specificity
Sara Fernandes et al.
JOURNAL OF BIOSCIENCES (2009)
Alteration of coenzyme specificity in halophilic NAD(P)+ glucose dehydrogenase by site-directed mutagenesis
C. Pire et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2009)
Site-saturation mutagenesis of formate dehydrogenase from Candida bodinii creating effective NADP(+)-dependent FDH enzymes
Weihua Wu et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2009)
Computational design of Candida boidinii xylose reductase for altered cofactor specificity
George A. Khoury et al.
PROTEIN SCIENCE (2009)
Structure-guided alteration of coenzyme specificity of formate dehydrogenase by saturation mutagenesis to enable efficient utilization of NADP+
Aggeliki Andreadeli et al.
FEBS JOURNAL (2008)
Structure-guided engineering of the coenzyme specificity of Pseudomonas fluorescens mannitol 2-dehydrogenase to enable efficient utilization of NAD(H) and NADP(H)
Patricia Bubner et al.
FEBS LETTERS (2008)
Altering coenzyme specificity of Pichia stipitis xylose reductase by the semi-rational approach CASTing
Ling Liang et al.
MICROBIAL CELL FACTORIES (2007)
Probing the determinants of coenzyme specificity in Peptostreptococcus asaccharolyticus glutamate dehydrogenase by site-directed mutagenesis
John B. Carrigan et al.
FEBS JOURNAL (2007)
Rational design of novel mutants of fungal 17β-hydroxy steroid dehydrogenase
Katja Kristan et al.
JOURNAL OF BIOTECHNOLOGY (2007)
Direct demonstration of an adaptive constraint
Stephen P. Miller et al.
SCIENCE (2006)
Crystal structure of NADP(H)-dependent 1,5-anhydro-D-fructose reductase from Sinorhizobium morelense at 2.2 Å resolution:: Construction of a NADH-accepting mutant and its application in rare sugar synthesis
Tresfore R. Dambe et al.
BIOCHEMISTRY (2006)
Determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial NAD(P)+-dependent malic enzyme -: Functional roles of glutamine 362
Ju-Yi Hsieh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Structure-guided engineering of xylitol dehydrogenase cosubstrate specificity
AH Ehrensberger et al.
STRUCTURE (2006)
Complete reversal of coenzyme specificity of isocitrate dehydrogenase from Haloferax volcanii
A Rodríguez-Arnedo et al.
PROTEIN JOURNAL (2005)
Catalytic hydroxylation in biphasic systems using CYP102A1 mutants
SC Maurer et al.
ADVANCED SYNTHESIS & CATALYSIS (2005)
Complete reversal of coenzyme specificity of xylitol dehydrogenase and increase of thermostability by the introduction of structural zinc
S Watanabe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography
B Petschacher et al.
BIOCHEMICAL JOURNAL (2005)
Conversion of cofactor specificities of alanine dehydrogenases by site-directed mutagenesis
H Ashida et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2004)
Identifying determinants of NADPH specificity in Baeyer-Villiger monooxygenases
NM Kamerbeek et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
Complete reversal of coenzyme specificity by concerted mutation of three consecutive residues in alcohol dehydrogenase
A Rosell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Relaxing the nicotinamide cofactor specificity of phosphite dehydrogenase by rational design
R Woodyer et al.
BIOCHEMISTRY (2003)
Engineering and characterization of a NADPH-utilizing cytochrome b5 reductase
CC Marohnic et al.
BIOCHEMISTRY (2003)
Modification of the nucleotide cofactor-binding site of cytochrome P-450 reductase to enhance turnover with NADH in vivo
CL Elmore et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Engineering of coenzyme specificity of formate dehydrogenase from Saccharomyces cerevisiae
AE Serov et al.
BIOCHEMICAL JOURNAL (2002)
Probing the determinants of coenzyme specificity in ferredoxin-NADP+ reductase by site-directed mutagenesis
M Medina et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A single mutation in the NAD-specific formate dehydrogenase from Candida methylica allows the enzyme to use NADP
N Gul-Karaguler et al.
BIOTECHNOLOGY LETTERS (2001)
Engineering of a functional human NADH-dependent cytochrome P450 system
O Döhr et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Inhibition of the thioredoxin-dependent activation of the NADP-malate dehydrogenase and cofactor specificity
I Schepens et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)