4.7 Article

4D Blood Flow Reconstruction Over the Entire Ventricle From Wall Motion and Blood Velocity Derived From Ultrasound Data

Journal

IEEE TRANSACTIONS ON MEDICAL IMAGING
Volume 34, Issue 11, Pages 2298-2308

Publisher

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMI.2015.2428932

Keywords

Doppler measurement; echocardiography

Funding

  1. Wellcome Trust IEH Award [102431]
  2. EPSRC [EP/H046410/1]
  3. Department of Health via the National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre award
  4. King's College London
  5. King's College Hospital NHS Foundation Trust
  6. Engineering and Physical Sciences Research Council [EP/H046410/1] Funding Source: researchfish
  7. EPSRC [EP/H046410/1] Funding Source: UKRI

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We demonstrate a new method to recover 4D blood flow over the entire ventricle from partial blood velocity measurements using multiple 3D + t colour Doppler images and ventricular wall motion estimated using 3D + t BMode images. We apply our approach to realistic simulated data to ascertain the ability of the method to deal with incomplete data, as typically happens in clinical practice. Experiments using synthetic data show that the use of wall motion improves velocity reconstruction, shows more accurate flow patterns and improves mean accuracy particularly when coverage of the ventricle is poor. The method was applied to patient data from 6 congenital cases, producing results consistent with the simulations. The use of wall motion produced more plausible flow patterns and reduced the reconstruction error in all patients.

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