Journal
ECS JOURNAL OF SOLID STATE SCIENCE AND TECHNOLOGY
Volume 7, Issue 7, Pages Q3196-Q3207Publisher
ELECTROCHEMICAL SOC INC
DOI: 10.1149/2.0291807jss
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Funding
- Ministry of Science and Technology (MOST) in [105-2221-E-002-232-MY3, 104-2628-E-002-014-MY3, 105-2119-M-002-004]
- National Taiwan University [NTU-107L900501]
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Biosensor research has been addressed as an interested field recently. Within different kinds of developed biosensing technologies, field-effect transistor (FET) based biosensors stand out due to their attractive features, such as ultra-sensitivity detection, mass-production capability, and low-cost manufacturing. To promote understandings of the FET based biosensing technology, in this review, its sensing mechanism is introduced, as well as major FET-based biosensing devices: ion sensitive field-effect transistor (ISFET), silicon nanowire, organic FET, graphene FET, and compound-semiconductor FET. In addition to FET-based biosensing devices, clinical applications, such as cardiovascular diseases (CVDs), cancers, diabetes, HIV, and DNA sequence, are also reviewed. In the end, several critical challenges of FET-based biosensing technology are discussed to envision next steps in healthcare technologies. (C) The Author(s) 2018. Published by ECS.
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