4.7 Review

Techniques for extraction and isolation of natural products: a comprehensive review

Journal

CHINESE MEDICINE
Volume 13, Issue -, Pages -

Publisher

BIOMED CENTRAL LTD
DOI: 10.1186/s13020-018-0177-x

Keywords

Natural products; Extraction; Isolation; Natural medicine; Chromatography; Phytochemical investigation

Funding

  1. Macau Science and Technology Development Fund [FDCT/042/2014/A1]
  2. Ministry of Science and Technology of China [2013DFM30080]
  3. University of Macau [MYRG2014-00162-ICMS-QRCM, MYRG2016-00046-ICMS-QRCM]

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Natural medicines were the only option for the prevention and treatment of human diseases for thousands of years. Natural products are important sources for drug development. The amounts of bioactive natural products in natural medicines are always fairly low. Today, it is very crucial to develop effective and selective methods for the extraction and isolation of those bioactive natural products. This paper intends to provide a comprehensive view of a variety of methods used in the extraction and isolation of natural products. This paper also presents the advantage, disadvantage and practical examples of conventional and modern techniques involved in natural products research.

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