Journal
JOURNAL OF GINSENG RESEARCH
Volume 42, Issue 2, Pages 225-228Publisher
KOREAN SOC GINSENG
DOI: 10.1016/j.jgr.2017.02.002
Keywords
cognitive impairment; Ginsenoside Rg5; HT22; neuroprotection; thermal stress
Funding
- Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries (IPET) through Export Promotion Technology Development Program - Ministry of Agriculture, Food and Rural Affairs (MAFRA) [316014031HD020]
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Education [2016R1D1A1A09917209]
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Our results suggested that thermal stress can lead to activation of hippocampal cell damage and reduction of memory-associated molecules in HT22 cells. These findings also provide a part of molecular rationale for the role of ginsenoside Rg5 as a potent cognitive impairment preventive compound in blocking the initiation of hippocampal damage. (C) 2017 The Korean Society of Ginseng, Published by Elsevier Korea LLC.
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