Journal
THERAPEUTIC DELIVERY
Volume 3, Issue 5, Pages 633-644Publisher
FUTURE SCI LTD
DOI: 10.4155/TDE.12.28
Keywords
-
Categories
Ask authors/readers for more resources
Drugs having bitter tastes cause low patient compliance. Many taste- masking techniques such as physical barrier coatings, chemical modification and sensory masking have been developed. Among chemical modification, the inclusion complexation of drugs with cyclodextrins (CyDs) can provide the effective bitter taste-masking effects without complicated formulation and/or delayed dissolution of drugs. Herein, we describe some quantitative methods to evaluate the taste-masking effects of CyD complexes with drugs in solution and the solid state. In addition, we introduce the recent applications of CyDs to excipients for taste masking against various bitter-taste drugs, as well as discuss the possible mechanisms for the taste-masking effect of CyD complexation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available