Journal
GENOME MEDICINE
Volume 10, Issue -, Pages -Publisher
BMC
DOI: 10.1186/s13073-018-0531-8
Keywords
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Categories
Funding
- Fundacio La Marato de TV3
- European Union's Horizon research and innovation programme [634143]
- European Research Council [682398]
- Severo Ochoa Centre of Excellence Award from the Spanish Ministry of Economy and Competitiveness (MINECO
- Government of Spain)
- CERCA (Generalitat de Catalunya)
- Agencia Estatal de Investigacion (AEI) [SAF2015-74072-JIN]
- Fondo Europeo de Desarrollo Regional (FEDER)
- FPI MINECO grant [BES-2013-063354]
- Ramon y Cajal fellowship [RYC-2013-14554]
- H2020 Societal Challenges Programme [634143] Funding Source: H2020 Societal Challenges Programme
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While tumor genome sequencing has become widely available in clinical and research settings, the interpretation of tumor somatic variants remains an important bottleneck. Here we present the Cancer Genome Interpreter, a versatile platform that automates the interpretation of newly sequenced cancer genomes, annotating the potential of alterations detected in tumors to act as drivers and their possible effect on treatment response. The results are organized in different levels of evidence according to current knowledge, which we envision can support a broad range of oncology use cases. The resource is publicly available at http://www.cancergenomeinterpreter.org.
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