Journal
CURRENT OPINION IN VIROLOGY
Volume 29, Issue -, Pages 87-100Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2018.03.007
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Funding
- Investigators in the Pathogenesis of Infectious Disease award from the Burroughs Wellcome Foundation
- NIAID [HHSN272200900041C]
- UMMS Center for Clinical and Translational Science
- Gilead Sciences Inc.
- Bill and Melinda Gates Foundation
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Viruses impose an immense burden on human health. With the goal of treating and preventing viral infections, researchers have carried out genetic screens to improve our understanding of viral dependencies and identify potential anti-viral strategies. The emergence of CRISPR genetic screening tools has facilitated this effort by enabling host-virus screens to be undertaken in a more versatile and fidelitous manner than previously possible. Here we review the growing number of CRISPR screens which continue to increase our understanding of host-virus interactions.
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