Differential Susceptibility Experiments: Going Beyond Correlational Evidence: Comment on Beyond Mental Health, Differential Susceptibility Articles

Reviewing the studies on differential susceptibility presented in this section, we argue that the time is ripe to go beyond correlational designs to differential susceptibility experiments. In such experiments, randomization prevents hidden moderator effects on the environment and guarantees the independence of moderator and outcome, while the environment is manipulated and assessed in standard ways. Correlational studies generate a priori expectations about crucial moderators (e.g., temperament, biological sensitivity, and genetics). We discuss the differential susceptibility experiments available up until now and conclude that these experiments are feasible and contribute in unique ways to our conceptions of differential susceptibility.